BRD-K15166186_TL_HRAS27 BRD-K15166186_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K15166186_TL_HRAS27 BRD-K15166186_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
BTG2 BTG family, member 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFD complement factor D (adipsin)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR1 early growth response 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
L1CAM L1 cell adhesion molecule
MT1X metallothionein 1X
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PRKCD protein kinase C, delta
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
WFDC2 WAP four-disulfide core domain 2
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADIRF adipogenesis regulatory factor
APOA1 apolipoprotein A-I
C1ORF116 chromosome 1 open reading frame 116
C6ORF62 chromosome 6 open reading frame 62
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCNA1 cyclin A1
CD200 CD200 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A2 collagen, type I, alpha 2
EIF5A eukaryotic translation initiation factor 5A
FLRT2 fibronectin leucine rich transmembrane protein 2
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ITGA6 integrin, alpha 6
LPAR6 lysophosphatidic acid receptor 6
MAST4 microtubule associated serine/threonine kinase family member 4
MTSS1 metastasis suppressor 1
NEB nebulin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSPH phosphoserine phosphatase
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RSAD2 radical S-adenosyl methionine domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)