BRD-K15086322_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

131 genes differentially expressed following the BRD-K15086322_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
AMOTL2 angiomotin like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARMCX2 armadillo repeat containing, X-linked 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
AXIN1 axin 1
BGN biglycan
CCDC92 coiled-coil domain containing 92
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDCA4 cell division cycle associated 4
CKS2 CDC28 protein kinase regulatory subunit 2
CLIC4 chloride intracellular channel 4
CTSG cathepsin G
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DENND2D DENN/MADD domain containing 2D
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPS8 epidermal growth factor receptor pathway substrate 8
FOLR1 folate receptor 1 (adult)
FZD7 frizzled class receptor 7
HOXB6 homeobox B6
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFITM1 interferon induced transmembrane protein 1
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KAZN kazrin, periplakin interacting protein
KDM5D lysine (K)-specific demethylase 5D
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LST1 leukocyte specific transcript 1
MAPT microtubule-associated protein tau
MET MET proto-oncogene, receptor tyrosine kinase
MFSD10 major facilitator superfamily domain containing 10
MYB v-myb avian myeloblastosis viral oncogene homolog
NEFH neurofilament, heavy polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
OAT ornithine aminotransferase
PEG10 paternally expressed 10
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PTGES prostaglandin E synthase
PTX3 pentraxin 3, long
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SKAP2 src kinase associated phosphoprotein 2
SLBP stem-loop binding protein
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLIT2 slit homolog 2 (Drosophila)
SMAD6 SMAD family member 6
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGOLN2 trans-golgi network protein 2
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
UGCG UDP-glucose ceramide glucosyltransferase
ZBTB18 zinc finger and BTB domain containing 18
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADA adenosine deaminase
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARG2 arginase 2
CADM1 cell adhesion molecule 1
CALML3 calmodulin-like 3
CD200 CD200 molecule
CD9 CD9 molecule
CLCA2 chloride channel accessory 2
CLCA4 chloride channel accessory 4
CLTB clathrin, light chain B
CLU clusterin
CPE carboxypeptidase E
CSRP1 cysteine and glycine-rich protein 1
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
DSG2 desmoglein 2
DUOX2 dual oxidase 2
EGFL6 EGF-like-domain, multiple 6
F11R F11 receptor
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBLN1 fibulin 1
GAGE3 G antigen 3
GLUL glutamate-ammonia ligase
GREM1 gremlin 1, DAN family BMP antagonist
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IGSF3 immunoglobulin superfamily, member 3
IL1RN interleukin 1 receptor antagonist
ITGA6 integrin, alpha 6
ITM2C integral membrane protein 2C
JAM2 junctional adhesion molecule 2
JCHAIN joining chain of multimeric IgA and IgM
KIAA0930 KIAA0930
KRT13 keratin 13, type I
KRT5 keratin 5, type II
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MEIS1 Meis homeobox 1
MMP12 matrix metallopeptidase 12
MMP3 matrix metallopeptidase 3
MTUS1 microtubule associated tumor suppressor 1
MYO1B myosin IB
NDN necdin, melanoma antigen (MAGE) family member
PALLD palladin, cytoskeletal associated protein
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRAME preferentially expressed antigen in melanoma
RAD23B RAD23 homolog B (S. cerevisiae)
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RFC5 replication factor C (activator 1) 5, 36.5kDa
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SCPEP1 serine carboxypeptidase 1
SMC1A structural maintenance of chromosomes 1A
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR3 small proline-rich protein 3
TBX3 T-box 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMOD1 tropomodulin 1
TP53I3 tumor protein p53 inducible protein 3
XIST X inactive specific transcript (non-protein coding)
ZW10 zw10 kinetochore protein