BRD-K15025317_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

92 genes differentially expressed following the BRD-K15025317_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACP5 acid phosphatase 5, tartrate resistant
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANPEP alanyl (membrane) aminopeptidase
BLVRB biliverdin reductase B
CCL13 chemokine (C-C motif) ligand 13
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD52 CD52 molecule
CNPY3 canopy FGF signaling regulator 3
CTSB cathepsin B
DDIT3 DNA-damage-inducible transcript 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EMC3 ER membrane protein complex subunit 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCMR Fc fragment of IgM receptor
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
LY86 lymphocyte antigen 86
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
NUCB2 nucleobindin 2
OPN3 opsin 3
PIR pirin (iron-binding nuclear protein)
PPAP2B phosphatidic acid phosphatase type 2B
PSAP prosaposin
RRBP1 ribosome binding protein 1
S100A12 S100 calcium binding protein A12
SELL selectin L
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TNC tenascin C
TXNRD1 thioredoxin reductase 1
TYROBP TYRO protein tyrosine kinase binding protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
CCND2 cyclin D2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
COL3A1 collagen, type III, alpha 1
CPE carboxypeptidase E
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
DLK1 delta-like 1 homolog (Drosophila)
DMD dystrophin
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPCAM epithelial cell adhesion molecule
FABP1 fatty acid binding protein 1, liver
FAM198B family with sequence similarity 198, member B
GJA1 gap junction protein, alpha 1, 43kDa
GRIA2 glutamate receptor, ionotropic, AMPA 2
HEPH hephaestin
HOXB6 homeobox B6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IRS1 insulin receptor substrate 1
ITM2A integral membrane protein 2A
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAP7 microtubule-associated protein 7
MB myoglobin
MECOM MDS1 and EVI1 complex locus
MEG3 maternally expressed 3 (non-protein coding)
MTA1 metastasis associated 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
ORM1 orosomucoid 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPW1 selenoprotein W, 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TSPAN8 tetraspanin 8