BRD-K14939371_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K14939371_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKRD10 ankyrin repeat domain 10
ANXA3 annexin A3
ANXA4 annexin A4
BASP1 brain abundant, membrane attached signal protein 1
BTBD3 BTB (POZ) domain containing 3
BTG2 BTG family, member 2
CD24 CD24 molecule
COL11A1 collagen, type XI, alpha 1
COL4A5 collagen, type IV, alpha 5
COL9A3 collagen, type IX, alpha 3
FOSL1 FOS-like antigen 1
FZD5 frizzled class receptor 5
GOLGA8B golgin A8 family, member B
GRN granulin
GSTM3 glutathione S-transferase mu 3 (brain)
HOXB6 homeobox B6
IL6ST interleukin 6 signal transducer
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KRCC1 lysine-rich coiled-coil 1
LAMP1 lysosomal-associated membrane protein 1
MAP7 microtubule-associated protein 7
MATN2 matrilin 2
NBPF10 neuroblastoma breakpoint family, member 10
NID2 nidogen 2 (osteonidogen)
PBX3 pre-B-cell leukemia homeobox 3
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
QPCT glutaminyl-peptide cyclotransferase
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SESN1 sestrin 1
SIK1 salt-inducible kinase 1
SLC38A1 solute carrier family 38, member 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TST thiosulfate sulfurtransferase (rhodanese)
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
AK4 adenylate kinase 4
AQP9 aquaporin 9
C1ORF115 chromosome 1 open reading frame 115
CRABP2 cellular retinoic acid binding protein 2
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
FBXL12 F-box and leucine-rich repeat protein 12
FCGBP Fc fragment of IgG binding protein
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GIMAP6 GTPase, IMAP family member 6
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
JMJD6 jumonji domain containing 6
KRT15 keratin 15, type I
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MDK midkine (neurite growth-promoting factor 2)
MMP9 matrix metallopeptidase 9
MSMO1 methylsterol monooxygenase 1
MT1X metallothionein 1X
MYH11 myosin, heavy chain 11, smooth muscle
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRKCB protein kinase C, beta
PTN pleiotrophin
S100A2 S100 calcium binding protein A2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SQLE squalene epoxidase