BRD-K14844937_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K14844937_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
CPT1A carnitine palmitoyltransferase 1A (liver)
FGFR3 fibroblast growth factor receptor 3
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
CA12 carbonic anhydrase XII
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER3 immediate early response 3
JUNB jun B proto-oncogene
KLK11 kallikrein-related peptidase 11
LDLR low density lipoprotein receptor
LTF lactotransferrin
MMP9 matrix metallopeptidase 9
MRPS2 mitochondrial ribosomal protein S2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TGFB1 transforming growth factor, beta 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPM4 tropomyosin 4