BRD-K14788918_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K14788918_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL6 B-cell CLL/lymphoma 6
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CD300A CD300a molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CYB561 cytochrome b561
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DPYSL3 dihydropyrimidinase-like 3
E2F2 E2F transcription factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EYA1 EYA transcriptional coactivator and phosphatase 1
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMOX1 heme oxygenase 1
KDM3A lysine (K)-specific demethylase 3A
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
LOX lysyl oxidase
LPAR1 lysophosphatidic acid receptor 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1M metallothionein 1M
MXI1 MAX interactor 1, dimerization protein
NAMPT nicotinamide phosphoribosyltransferase
NOTCH1 notch 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLAGL1 pleiomorphic adenoma gene-like 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PXDN peroxidasin
PXMP2 peroxisomal membrane protein 2, 22kDa
RIOK3 RIO kinase 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPAG4 sperm associated antigen 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STC1 stanniocalcin 1
TCF4 transcription factor 4
TM4SF1 transmembrane 4 L six family member 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CALR calreticulin
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC11A C-type lectin domain family 11, member A
CTSG cathepsin G
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPP4 dipeptidyl-peptidase 4
FBXO11 F-box protein 11
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
KIF20A kinesin family member 20A
KRT17 keratin 17, type I
LRRC16A leucine rich repeat containing 16A
MCOLN1 mucolipin 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAX5 paired box 5
PCDH7 protocadherin 7
PLK1 polo-like kinase 1
PLS3 plastin 3
PODXL podocalyxin-like
RNF167 ring finger protein 167
SLC39A8 solute carrier family 39 (zinc transporter), member 8
STAT1 signal transducer and activator of transcription 1, 91kDa
TACSTD2 tumor-associated calcium signal transducer 2
THSD7A thrombospondin, type I, domain containing 7A
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TPD52 tumor protein D52