BRD-K14200658_Syrosingopine_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K14200658_Syrosingopine_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BEX4 brain expressed, X-linked 4
COG7 component of oligomeric golgi complex 7
CRABP2 cellular retinoic acid binding protein 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
ESRP1 epithelial splicing regulatory protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4C histone cluster 1, H4c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFNAR1 interferon (alpha, beta and omega) receptor 1
ISOC1 isochorismatase domain containing 1
KRT6B keratin 6B, type II
KRT81 keratin 81, type II
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPIPB3 nuclear pore complex interacting protein family, member B3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLXNC1 plexin C1
SRRM2 serine/arginine repetitive matrix 2
TPD52L1 tumor protein D52-like 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VLDLR very low density lipoprotein receptor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ADGRE5 adhesion G protein-coupled receptor E5
AK4 adenylate kinase 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
ASS1 argininosuccinate synthase 1
CCL2 chemokine (C-C motif) ligand 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL14 chemokine (C-X-C motif) ligand 14
DEFB1 defensin, beta 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXF1 forkhead box F1
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPI glucose-6-phosphate isomerase
HN1 hematological and neurological expressed 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
OLFM1 olfactomedin 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLBD1 phospholipase B domain containing 1
RPS11 ribosomal protein S11
SC5D sterol-C5-desaturase
SCML1 sex comb on midleg-like 1 (Drosophila)
TACSTD2 tumor-associated calcium signal transducer 2
TBCB tubulin folding cofactor B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THY1 Thy-1 cell surface antigen
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAPPC4 trafficking protein particle complex 4
TSPAN8 tetraspanin 8
TUBA4A tubulin, alpha 4a
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24