BRD-K14109347_LY2603618_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K14109347_LY2603618_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
BCHE butyrylcholinesterase
BCL6 B-cell CLL/lymphoma 6
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CREG1 cellular repressor of E1A-stimulated genes 1
CSTA cystatin A (stefin A)
GAGE3 G antigen 3
GDF15 growth differentiation factor 15
GFOD1 glucose-fructose oxidoreductase domain containing 1
H2BFS H2B histone family, member S (pseudogene)
HAL histidine ammonia-lyase
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
METTL7A methyltransferase like 7A
REG1A regenerating islet-derived 1 alpha
RPS27L ribosomal protein S27-like
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SSX1 synovial sarcoma, X breakpoint 1
TMEM110 transmembrane protein 110

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALCAM activated leukocyte cell adhesion molecule
C3ORF14 chromosome 3 open reading frame 14
CAPG capping protein (actin filament), gelsolin-like
CD24 CD24 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLIC3 chloride intracellular channel 3
COL5A1 collagen, type V, alpha 1
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DBN1 drebrin 1
DEPTOR DEP domain containing MTOR-interacting protein
EFHD1 EF-hand domain family, member D1
FGFR3 fibroblast growth factor receptor 3
FHOD3 formin homology 2 domain containing 3
GSTM3 glutathione S-transferase mu 3 (brain)
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
ITGB1BP1 integrin beta 1 binding protein 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT19 keratin 19, type I
MGLL monoglyceride lipase
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MME membrane metallo-endopeptidase
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MX1 MX dynamin-like GTPase 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OXTR oxytocin receptor
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PLAC8 placenta-specific 8
PROM1 prominin 1
RTN2 reticulon 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDC1 syndecan 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD7 SMAD family member 7
SSBP2 single-stranded DNA binding protein 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP8 vesicle-associated membrane protein 8
VCAM1 vascular cell adhesion molecule 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
XYLT1 xylosyltransferase I