BRD-K13566078_BMS-345541_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K13566078_BMS-345541_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ANXA1 annexin A1
BIK BCL2-interacting killer (apoptosis-inducing)
CCL19 chemokine (C-C motif) ligand 19
COCH cochlin
CSRP1 cysteine and glycine-rich protein 1
CTTN cortactin
DNM1L dynamin 1-like
EAPP E2F-associated phosphoprotein
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM129A family with sequence similarity 129, member A
GATA6 GATA binding protein 6
IGFBP7 insulin-like growth factor binding protein 7
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRX5 iroquois homeobox 5
LAMP5 lysosomal-associated membrane protein family, member 5
LTF lactotransferrin
MRPS30 mitochondrial ribosomal protein S30
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NOV nephroblastoma overexpressed
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RHOH ras homolog family member H
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SRPX sushi-repeat containing protein, X-linked
SST somatostatin
TAGLN2 transgelin 2
TOB1 transducer of ERBB2, 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ARID5B AT rich interactive domain 5B (MRF1-like)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL4 chemokine (C-C motif) ligand 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
EMX2 empty spiracles homeobox 2
FBXW2 F-box and WD repeat domain containing 2
GSAP gamma-secretase activating protein
HBB hemoglobin, beta
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
IGHM immunoglobulin heavy constant mu
MTSS1 metastasis suppressor 1
NT5E 5'-nucleotidase, ecto (CD73)
OSBPL3 oxysterol binding protein-like 3
PLAT plasminogen activator, tissue
RBBP8 retinoblastoma binding protein 8
S100P S100 calcium binding protein P
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMC1A structural maintenance of chromosomes 1A
SPINK1 serine peptidase inhibitor, Kazal type 1
SULF1 sulfatase 1
TANK TRAF family member-associated NFKB activator
TBC1D31 TBC1 domain family, member 31
TMEM2 transmembrane protein 2
TOX3 TOX high mobility group box family member 3
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)