BRD-K13566078_BMS-345541_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-K13566078_BMS-345541_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BST2 bone marrow stromal cell antigen 2
CAV2 caveolin 2
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD48 CD48 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CLDN10 claudin 10
COCH cochlin
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
DEFB1 defensin, beta 1
DPT dermatopontin
DUSP6 dual specificity phosphatase 6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FBXO11 F-box protein 11
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GLB1L2 galactosidase, beta 1-like 2
GSTA1 glutathione S-transferase alpha 1
GSTM3 glutathione S-transferase mu 3 (brain)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXA5 homeobox A5
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM3 interferon induced transmembrane protein 3
ISG15 ISG15 ubiquitin-like modifier
ISYNA1 inositol-3-phosphate synthase 1
ITGAV integrin, alpha V
ITM2A integral membrane protein 2A
KLK11 kallikrein-related peptidase 11
KRT23 keratin 23, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPAR2 lysophosphatidic acid receptor 2
LTF lactotransferrin
LYZ lysozyme
MDK midkine (neurite growth-promoting factor 2)
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MPO myeloperoxidase
MXRA5 matrix-remodelling associated 5
NPTX2 neuronal pentraxin II
NQO1 NAD(P)H dehydrogenase, quinone 1
OLFM4 olfactomedin 4
PDZK1IP1 PDZK1 interacting protein 1
PELI1 pellino E3 ubiquitin protein ligase 1
PRKCB protein kinase C, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPARCL1 SPARC-like 1 (hevin)
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
STEAP1 six transmembrane epithelial antigen of the prostate 1
STS steroid sulfatase (microsomal), isozyme S
SUB1 SUB1 homolog (S. cerevisiae)
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYNM synemin, intermediate filament protein
TGFB1 transforming growth factor, beta 1
TMEM14B transmembrane protein 14B
TUBB2A tubulin, beta 2A class IIa
TUSC3 tumor suppressor candidate 3
VTCN1 V-set domain containing T cell activation inhibitor 1
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKB aurora kinase B
CCND1 cyclin D1
CEMIP cell migration inducing protein, hyaluronan binding
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMX2 empty spiracles homeobox 2
FBXW2 F-box and WD repeat domain containing 2
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMGA2 high mobility group AT-hook 2
IGFBP4 insulin-like growth factor binding protein 4
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
KDM5D lysine (K)-specific demethylase 5D
KIAA0355 KIAA0355
KIF14 kinesin family member 14
KRT7 keratin 7, type II
NBPF10 neuroblastoma breakpoint family, member 10
NUP62 nucleoporin 62kDa
PDE4B phosphodiesterase 4B, cAMP-specific
RPL31 ribosomal protein L31
RSL1D1 ribosomal L1 domain containing 1
SLC38A2 solute carrier family 38, member 2
SLK STE20-like kinase
SMAGP small cell adhesion glycoprotein
SNAP25 synaptosomal-associated protein, 25kDa
TBC1D31 TBC1 domain family, member 31
TKTL1 transketolase-like 1
TMEM2 transmembrane protein 2
TOPBP1 topoisomerase (DNA) II binding protein 1
TPM4 tropomyosin 4
TSPAN5 tetraspanin 5
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZNF274 zinc finger protein 274