BRD-K13566078_BMS-345541_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K13566078_BMS-345541_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP9 aquaporin 9
ARG1 arginase 1
ARHGAP29 Rho GTPase activating protein 29
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CKB creatine kinase, brain
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EREG epiregulin
GSTP1 glutathione S-transferase pi 1
HP haptoglobin
IGL immunoglobulin lambda locus
KLF6 Kruppel-like factor 6
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC17 leucine rich repeat containing 17
MAOB monoamine oxidase B
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTF2 metal response element binding transcription factor 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
OAT ornithine aminotransferase
ORM1 orosomucoid 1
PTN pleiotrophin
S100A12 S100 calcium binding protein A12
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SOX4 SRY (sex determining region Y)-box 4
TACSTD2 tumor-associated calcium signal transducer 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AQP3 aquaporin 3 (Gill blood group)
CEMIP cell migration inducing protein, hyaluronan binding
EMX2 empty spiracles homeobox 2
FCGBP Fc fragment of IgG binding protein
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
HOPX HOP homeobox
MFAP5 microfibrillar associated protein 5
NRCAM neuronal cell adhesion molecule
PDZD2 PDZ domain containing 2
PTGIS prostaglandin I2 (prostacyclin) synthase
S100A8 S100 calcium binding protein A8
SCRG1 stimulator of chondrogenesis 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)