BRD-K13390322_AT-7519_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K13390322_AT-7519_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
CD24 CD24 molecule
CFB complement factor B
COPZ2 coatomer protein complex, subunit zeta 2
CP ceruloplasmin (ferroxidase)
CRYAB crystallin, alpha B
CXCL10 chemokine (C-X-C motif) ligand 10
EMP3 epithelial membrane protein 3
EREG epiregulin
GLIPR1 GLI pathogenesis-related 1
GPC4 glypican 4
GPNMB glycoprotein (transmembrane) nmb
HP haptoglobin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IRX5 iroquois homeobox 5
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT14 keratin 14, type I
LAGE3 L antigen family, member 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
MAOB monoamine oxidase B
MCL1 myeloid cell leukemia 1
MIA melanoma inhibitory activity
NRIP1 nuclear receptor interacting protein 1
PNKP polynucleotide kinase 3'-phosphatase
PRAME preferentially expressed antigen in melanoma
PXMP2 peroxisomal membrane protein 2, 22kDa
QPCT glutaminyl-peptide cyclotransferase
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN4 tetraspanin 4
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
AGR2 anterior gradient 2
BASP1 brain abundant, membrane attached signal protein 1
CALB1 calbindin 1, 28kDa
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CEMIP cell migration inducing protein, hyaluronan binding
COG2 component of oligomeric golgi complex 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATA3 GATA binding protein 3
HILPDA hypoxia inducible lipid droplet-associated
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGL immunoglobulin lambda locus
IRS2 insulin receptor substrate 2
MAT2A methionine adenosyltransferase II, alpha
MMD monocyte to macrophage differentiation-associated
MYH11 myosin, heavy chain 11, smooth muscle
NUP85 nucleoporin 85kDa
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PNMA1 paraneoplastic Ma antigen 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
S100P S100 calcium binding protein P
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMYD2 SET and MYND domain containing 2
SNAP25 synaptosomal-associated protein, 25kDa
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TMEM100 transmembrane protein 100
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8
WT1 Wilms tumor 1