BRD-K13390322_AT-7519_SKBR3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

257 genes differentially expressed following the BRD-K13390322_AT-7519_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACOT13 acyl-CoA thioesterase 13
ADD3 adducin 3 (gamma)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMPD3 adenosine monophosphate deaminase 3
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ATF3 activating transcription factor 3
BEX1 brain expressed, X-linked 1
BID BH3 interacting domain death agonist
BMP2 bone morphogenetic protein 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BSG basigin (Ok blood group)
BTG2 BTG family, member 2
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CCL20 chemokine (C-C motif) ligand 20
CD3D CD3d molecule, delta (CD3-TCR complex)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CELF2 CUGBP, Elav-like family member 2
CEP350 centrosomal protein 350kDa
CEP70 centrosomal protein 70kDa
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CKB creatine kinase, brain
CLC Charcot-Leyden crystal galectin
COL4A5 collagen, type IV, alpha 5
COL6A1 collagen, type VI, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DEPTOR DEP domain containing MTOR-interacting protein
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
EXPH5 exophilin 5
FAM46A family with sequence similarity 46, member A
FAM8A1 family with sequence similarity 8, member A1
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXC1 forkhead box C1
FTO fat mass and obesity associated
GADD45B growth arrest and DNA-damage-inducible, beta
GBE1 glucan (1,4-alpha-), branching enzyme 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GOLM1 golgi membrane protein 1
GPM6B glycoprotein M6B
GPX3 glutathione peroxidase 3
GUSBP3 glucuronidase, beta pseudogene 3
HACD1 3-hydroxyacyl-CoA dehydratase 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC6 histone deacetylase 6
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IFRD2 interferon-related developmental regulator 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
IGLL1 immunoglobulin lambda-like polypeptide 1
IL2RG interleukin 2 receptor, gamma
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAV integrin, alpha V
ITM2A integral membrane protein 2A
ITM2C integral membrane protein 2C
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
KLF9 Kruppel-like factor 9
LAGE3 L antigen family, member 3
LAMP3 lysosomal-associated membrane protein 3
LRRC17 leucine rich repeat containing 17
MAOA monoamine oxidase A
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MBP myelin basic protein
MEF2C myocyte enhancer factor 2C
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
MT1E metallothionein 1E
MT1F metallothionein 1F
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
NME4 NME/NM23 nucleoside diphosphate kinase 4
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAM peptidylglycine alpha-amidating monooxygenase
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM1 PDZ and LIM domain 1
PEG3 paternally expressed 3
PER1 period circadian clock 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLVAP plasmalemma vesicle associated protein
PTER phosphotriesterase related
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRD protein tyrosine phosphatase, receptor type, D
PVALB parvalbumin
RBP4 retinol binding protein 4, plasma
RHOBTB3 Rho-related BTB domain containing 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SDC2 syndecan 2
SEPT6 septin 6
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMC1A structural maintenance of chromosomes 1A
SPARCL1 SPARC-like 1 (hevin)
SRPR signal recognition particle receptor (docking protein)
STC1 stanniocalcin 1
STK26 serine/threonine protein kinase 26
TF transferrin
TGFA transforming growth factor, alpha
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
TLE2 transducin-like enhancer of split 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNNT1 troponin T type 1 (skeletal, slow)
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TRBC1 T cell receptor beta constant 1
TSPAN1 tetraspanin 1
TTC3 tetratricopeptide repeat domain 3
TXNIP thioredoxin interacting protein
VWA5A von Willebrand factor A domain containing 5A
WDR45 WD repeat domain 45
WSB1 WD repeat and SOCS box containing 1
XIST X inactive specific transcript (non-protein coding)
ZIC1 Zic family member 1
ZNF331 zinc finger protein 331
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AHNAK AHNAK nucleoprotein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AQP3 aquaporin 3 (Gill blood group)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BICC1 BicC family RNA binding protein 1
BLMH bleomycin hydrolase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CANT1 calcium activated nucleotidase 1
CASC3 cancer susceptibility candidate 3
CCNA2 cyclin A2
CD24 CD24 molecule
CDC20 cell division cycle 20
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK1 cyclin-dependent kinase 1
CHMP7 charged multivesicular body protein 7
CKS1B CDC28 protein kinase regulatory subunit 1B
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CRIP1 cysteine-rich protein 1 (intestinal)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCK deoxycytidine kinase
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
FABP7 fatty acid binding protein 7, brain
FGFR2 fibroblast growth factor receptor 2
FOXJ3 forkhead box J3
GCH1 GTP cyclohydrolase 1
GPX2 glutathione peroxidase 2
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
ILF3 interleukin enhancer binding factor 3, 90kDa
INHBB inhibin, beta B
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
KIAA0355 KIAA0355
KLF4 Kruppel-like factor 4 (gut)
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT23 keratin 23, type I
KRT7 keratin 7, type II
MALT1 MALT1 paracaspase
MARCKS myristoylated alanine-rich protein kinase C substrate
MED24 mediator complex subunit 24
MELK maternal embryonic leucine zipper kinase
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP7 matrix metallopeptidase 7
MSL1 male-specific lethal 1 homolog (Drosophila)
MTA1 metastasis associated 1
MTERF3 mitochondrial transcription termination factor 3
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NET1 neuroepithelial cell transforming 1
NKX3-1 NK3 homeobox 1
NOP56 NOP56 ribonucleoprotein
NPY1R neuropeptide Y receptor Y1
NUP62 nucleoporin 62kDa
OPN3 opsin 3
ORC1 origin recognition complex, subunit 1
PCNA proliferating cell nuclear antigen
PHF20 PHD finger protein 20
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PNP purine nucleoside phosphorylase
PRSS2 protease, serine, 2 (trypsin 2)
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
RAB22A RAB22A, member RAS oncogene family
RAE1 ribonucleic acid export 1
RBM38 RNA binding motif protein 38
RFC2 replication factor C (activator 1) 2, 40kDa
RPS4Y1 ribosomal protein S4, Y-linked 1
RRBP1 ribosome binding protein 1
RRM2 ribonucleotide reductase M2
S100A7 S100 calcium binding protein A7
SCAND1 SCAN domain containing 1
SEPT9 septin 9
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLPI secretory leukocyte peptidase inhibitor
SMC4 structural maintenance of chromosomes 4
SMCO4 single-pass membrane protein with coiled-coil domains 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SRSF6 serine/arginine-rich splicing factor 6
ST7 suppression of tumorigenicity 7
STAU1 staufen double-stranded RNA binding protein 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBL2 transducin (beta)-like 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM9SF3 transmembrane 9 superfamily member 3
TMEM97 transmembrane protein 97
TOP2A topoisomerase (DNA) II alpha 170kDa
TXLNA taxilin alpha
TYMS thymidylate synthetase
UBE2I ubiquitin-conjugating enzyme E2I
UBE3C ubiquitin protein ligase E3C
USP22 ubiquitin specific peptidase 22
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
WIPF2 WAS/WASL interacting protein family, member 2
XBP1 X-box binding protein 1
YBX3 Y box binding protein 3
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF217 zinc finger protein 217
ZWINT ZW10 interacting kinetochore protein