BRD-K13390322_AT-7519_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K13390322_AT-7519_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C3 complement component 3
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COL15A1 collagen, type XV, alpha 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOLR1 folate receptor 1 (adult)
GJA1 gap junction protein, alpha 1, 43kDa
GPM6B glycoprotein M6B
GPX3 glutathione peroxidase 3
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXB2 homeobox B2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFRD2 interferon-related developmental regulator 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
L1CAM L1 cell adhesion molecule
NEFH neurofilament, heavy polypeptide
PEG10 paternally expressed 10
PNMA2 paraneoplastic Ma antigen 2
POSTN periostin, osteoblast specific factor
PSPH phosphoserine phosphatase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGCE sarcoglycan, epsilon
SST somatostatin

decreased expression

Symbol Name
ADM adrenomedullin
ATF5 activating transcription factor 5
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAB39 calcium binding protein 39
CCL19 chemokine (C-C motif) ligand 19
CD3D CD3d molecule, delta (CD3-TCR complex)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN3 claudin 3
CSTA cystatin A (stefin A)
CXCL12 chemokine (C-X-C motif) ligand 12
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP4 dual specificity phosphatase 4
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAS Fas cell surface death receptor
GDF15 growth differentiation factor 15
GIMAP6 GTPase, IMAP family member 6
HBEGF heparin-binding EGF-like growth factor
HOXA10 homeobox A10
HSPA2 heat shock 70kDa protein 2
IGFBP5 insulin-like growth factor binding protein 5
JMJD6 jumonji domain containing 6
LDHB lactate dehydrogenase B
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MYB v-myb avian myeloblastosis viral oncogene homolog
NR4A2 nuclear receptor subfamily 4, group A, member 2
RHOBTB3 Rho-related BTB domain containing 3
S100A11 S100 calcium binding protein A11
SCGB2A2 secretoglobin, family 2A, member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
TLR4 toll-like receptor 4
TSPYL5 TSPY-like 5