BRD-K13390322_AT-7519_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

155 genes differentially expressed following the BRD-K13390322_AT-7519_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACE2 angiotensin I converting enzyme 2
ADD3 adducin 3 (gamma)
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMT aminomethyltransferase
AQP9 aquaporin 9
BAG6 BCL2-associated athanogene 6
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL20 chemokine (C-C motif) ligand 20
CD59 CD59 molecule, complement regulatory protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CES1 carboxylesterase 1
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
COL1A2 collagen, type I, alpha 2
CPM carboxypeptidase M
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
EGF epidermal growth factor
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
ENO2 enolase 2 (gamma, neuronal)
EPCAM epithelial cell adhesion molecule
F13A1 coagulation factor XIII, A1 polypeptide
FAM171A1 family with sequence similarity 171, member A1
FASN fatty acid synthase
FCGRT Fc fragment of IgG, receptor, transporter, alpha
G0S2 G0/G1 switch 2
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
ISG15 ISG15 ubiquitin-like modifier
KIAA0226L KIAA0226-like
LCN2 lipocalin 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LZTS3 leucine zipper, putative tumor suppressor family member 3
MMP9 matrix metallopeptidase 9
NMU neuromedin U
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PENK proenkephalin
PRKACB protein kinase, cAMP-dependent, catalytic, beta
QPCT glutaminyl-peptide cyclotransferase
RGS4 regulator of G-protein signaling 4
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPRY4 sprouty homolog 4 (Drosophila)
SRPX2 sushi-repeat containing protein, X-linked 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
THY1 Thy-1 cell surface antigen
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WFDC2 WAP four-disulfide core domain 2
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AIM1 absent in melanoma 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BAMBI BMP and activin membrane-bound inhibitor
CCNF cyclin F
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLU clusterin
COIL coilin
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EFNA1 ephrin-A1
EGR2 early growth response 2
ESR1 estrogen receptor 1
FAM208B family with sequence similarity 208, member B
FHL1 four and a half LIM domains 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GSPT2 G1 to S phase transition 2
HOPX HOP homeobox
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER5 immediate early response 5
IGFBP4 insulin-like growth factor binding protein 4
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JADE2 jade family PHD finger 2
KLF4 Kruppel-like factor 4 (gut)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MED13 mediator complex subunit 13
MREG melanoregulin
MT1H metallothionein 1H
MT1X metallothionein 1X
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NET1 neuroepithelial cell transforming 1
NFIL3 nuclear factor, interleukin 3 regulated
NOL11 nucleolar protein 11
NOTCH2 notch 2
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRPF4 pre-mRNA processing factor 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RBM47 RNA binding motif protein 47
RHOB ras homolog family member B
RND3 Rho family GTPase 3
RNMT RNA (guanine-7-) methyltransferase
RPP38 ribonuclease P/MRP 38kDa subunit
SCGB2A2 secretoglobin, family 2A, member 2
SERTAD2 SERTA domain containing 2
SESN1 sestrin 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMG8 SMG8 nonsense mediated mRNA decay factor
SNX11 sorting nexin 11
SOX4 SRY (sex determining region Y)-box 4
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBP TATA box binding protein
TBPL1 TBP-like 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF1 trefoil factor 1
TGIF1 TGFB-induced factor homeobox 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNPO1 transportin 1
TOB1 transducer of ERBB2, 1
TSKU tsukushi, small leucine rich proteoglycan
TUBD1 tubulin, delta 1
UMPS uridine monophosphate synthetase
USP1 ubiquitin specific peptidase 1
VEZF1 vascular endothelial zinc finger 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF217 zinc finger protein 217