BRD-K13390322_AT-7519_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

122 genes differentially expressed following the BRD-K13390322_AT-7519_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AEBP1 AE binding protein 1
CD59 CD59 molecule, complement regulatory protein
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L2 chitinase 3-like 2
COL1A2 collagen, type I, alpha 2
COL6A3 collagen, type VI, alpha 3
CP ceruloplasmin (ferroxidase)
CSTA cystatin A (stefin A)
CYB5A cytochrome b5 type A (microsomal)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERAP1 endoplasmic reticulum aminopeptidase 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FST follistatin
GK glycerol kinase
GPM6A glycoprotein M6A
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LTA4H leukotriene A4 hydrolase
LTBP1 latent transforming growth factor beta binding protein 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
NEBL nebulette
NLGN4X neuroligin 4, X-linked
NTS neurotensin
P3H2 prolyl 3-hydroxylase 2
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PIP prolactin-induced protein
PIR pirin (iron-binding nuclear protein)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RBKS ribokinase
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TFRC transferrin receptor
TMEM45A transmembrane protein 45A
TPM4 tropomyosin 4
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
AMOTL2 angiomotin like 2
AURKA aurora kinase A
AUTS2 autism susceptibility candidate 2
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCNE2 cyclin E2
CCNG2 cyclin G2
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CSNK1E casein kinase 1, epsilon
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPT dermatopontin
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFNA1 ephrin-A1
EIF5 eukaryotic translation initiation factor 5
FOXJ3 forkhead box J3
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA2 GATA binding protein 2
GEM GTP binding protein overexpressed in skeletal muscle
GRB10 growth factor receptor-bound protein 10
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IER5 immediate early response 5
KAT6A K(lysine) acetyltransferase 6A
KIAA0907 KIAA0907
KLF4 Kruppel-like factor 4 (gut)
LIPT1 lipoyltransferase 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKS myristoylated alanine-rich protein kinase C substrate
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MED17 mediator complex subunit 17
MYC v-myc avian myelocytomatosis viral oncogene homolog
N4BP2L2 NEDD4 binding protein 2-like 2
NET1 neuroepithelial cell transforming 1
NFIL3 nuclear factor, interleukin 3 regulated
NOTCH2NL notch 2 N-terminal like
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
OLFM4 olfactomedin 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RAE1 ribonucleic acid export 1
RHOB ras homolog family member B
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SERTAD2 SERTA domain containing 2
SESN1 sestrin 1
SMAD7 SMAD family member 7
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBP TATA box binding protein
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
TXNDC9 thioredoxin domain containing 9
UGCG UDP-glucose ceramide glucosyltransferase
VGLL4 vestigial-like family member 4
WEE1 WEE1 G2 checkpoint kinase
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF217 zinc finger protein 217