BRD-K13390322_AT-7519_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K13390322_AT-7519_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASPN asporin
BPTF bromodomain PHD finger transcription factor
CADM1 cell adhesion molecule 1
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL4A5 collagen, type IV, alpha 5
CRABP2 cellular retinoic acid binding protein 2
FBLN1 fibulin 1
FOLR1 folate receptor 1 (adult)
GLG1 golgi glycoprotein 1
GPC3 glypican 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IDO1 indoleamine 2,3-dioxygenase 1
MOK MOK protein kinase
OLFM4 olfactomedin 4
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PEG10 paternally expressed 10
PGC progastricsin (pepsinogen C)
PIEZO2 piezo-type mechanosensitive ion channel component 2
PRKCI protein kinase C, iota
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRSS2 protease, serine, 2 (trypsin 2)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TM4SF1 transmembrane 4 L six family member 1
TUBB6 tubulin, beta 6 class V

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF5 activating transcription factor 5
CCNF cyclin F
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL8 chemokine (C-X-C motif) ligand 8
ETV1 ets variant 1
FCGBP Fc fragment of IgG binding protein
GADD45B growth arrest and DNA-damage-inducible, beta
GALC galactosylceramidase
GLUL glutamate-ammonia ligase
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IER3 immediate early response 3
JUN jun proto-oncogene
KRT13 keratin 13, type I
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAT2A methionine adenosyltransferase II, alpha
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NUP50 nucleoporin 50kDa
PDGFA platelet-derived growth factor alpha polypeptide
PROM1 prominin 1
RNASET2 ribonuclease T2
S100A8 S100 calcium binding protein A8
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SPRR3 small proline-rich protein 3
STAR steroidogenic acute regulatory protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)