BRD-K13390322_AT-7519_HEPG2_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K13390322_AT-7519_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADRB2 adrenoceptor beta 2, surface
APOD apolipoprotein D
ATF3 activating transcription factor 3
C2CD2 C2 calcium-dependent domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
CYTIP cytohesin 1 interacting protein
DUSP22 dual specificity phosphatase 22
E2F2 E2F transcription factor 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAGE3 G antigen 3
KIF3B kinesin family member 3B
KRT5 keratin 5, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NCALD neurocalcin delta
NEFL neurofilament, light polypeptide
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDLIM5 PDZ and LIM domain 5
PNMAL1 paraneoplastic Ma antigen family-like 1
PRAME preferentially expressed antigen in melanoma
RCAN2 regulator of calcineurin 2
RGS4 regulator of G-protein signaling 4
SATB1 SATB homeobox 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPP1 secreted phosphoprotein 1
SRGN serglycin
STXBP1 syntaxin binding protein 1
TGFBR3 transforming growth factor, beta receptor III
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
VIM vimentin
VSNL1 visinin-like 1

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ANPEP alanyl (membrane) aminopeptidase
C1R complement component 1, r subcomponent
CADM1 cell adhesion molecule 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFB complement factor B
CRELD2 cysteine-rich with EGF-like domains 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FADS1 fatty acid desaturase 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
H1F0 H1 histone family, member 0
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLK11 kallikrein-related peptidase 11
KLK12 kallikrein-related peptidase 12
LAMA3 laminin, alpha 3
MB myoglobin
NEB nebulin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TSPAN8 tetraspanin 8