BRD-K13390322_AT-7519_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K13390322_AT-7519_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCHE butyrylcholinesterase
BST2 bone marrow stromal cell antigen 2
CCND2 cyclin D2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CFH complement factor H
CTSH cathepsin H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ETV1 ets variant 1
FLRT2 fibronectin leucine rich transmembrane protein 2
GREM1 gremlin 1, DAN family BMP antagonist
IFI6 interferon, alpha-inducible protein 6
ISG15 ISG15 ubiquitin-like modifier
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0226L KIAA0226-like
LAPTM4B lysosomal protein transmembrane 4 beta
NMU neuromedin U
NREP neuronal regeneration related protein
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PFKM phosphofructokinase, muscle
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRE protein tyrosine phosphatase, receptor type, E
PXDN peroxidasin
SCG5 secretogranin V
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D4 TBC1 domain family, member 4
TMEM47 transmembrane protein 47
TSPAN13 tetraspanin 13
TUBA1A tubulin, alpha 1a
XAF1 XIAP associated factor 1

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
CANT1 calcium activated nucleotidase 1
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DLC1 DLC1 Rho GTPase activating protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
GADD45A growth arrest and DNA-damage-inducible, alpha
IER3 immediate early response 3
JADE2 jade family PHD finger 2
JUN jun proto-oncogene
MARCKS myristoylated alanine-rich protein kinase C substrate
MED13 mediator complex subunit 13
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
RHOB ras homolog family member B
SCGB2A2 secretoglobin, family 2A, member 2
SERTAD2 SERTA domain containing 2
SPEN spen family transcriptional repressor
STC1 stanniocalcin 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
TSC22D2 TSC22 domain family, member 2
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZFP36 ZFP36 ring finger protein