BRD-K13390322_AT-7519_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K13390322_AT-7519_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AREG amphiregulin
ATF3 activating transcription factor 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BTG3 BTG family, member 3
CAV1 caveolin 1, caveolae protein, 22kDa
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CKB creatine kinase, brain
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
DLD dihydrolipoamide dehydrogenase
DPT dermatopontin
DSP desmoplakin
DUSP22 dual specificity phosphatase 22
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
ENO2 enolase 2 (gamma, neuronal)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GAL galanin/GMAP prepropeptide
GEM GTP binding protein overexpressed in skeletal muscle
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMD monocyte to macrophage differentiation-associated
MMP1 matrix metallopeptidase 1
ODC1 ornithine decarboxylase 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
RBP1 retinol binding protein 1, cellular
SCGB2A2 secretoglobin, family 2A, member 2
SESN1 sestrin 1
SFN stratifin
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPON2 spondin 2, extracellular matrix protein
STC2 stanniocalcin 2
TFPI2 tissue factor pathway inhibitor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ASF1A anti-silencing function 1A histone chaperone
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
BCAS1 breast carcinoma amplified sequence 1
CDH19 cadherin 19, type 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DUOX2 dual oxidase 2
EPHA3 EPH receptor A3
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM46A family with sequence similarity 46, member A
GPX2 glutathione peroxidase 2
HNMT histamine N-methyltransferase
KLHL9 kelch-like family member 9
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NNMT nicotinamide N-methyltransferase
PLEKHA5 pleckstrin homology domain containing, family A member 5
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAB13 RAB13, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RHOBTB3 Rho-related BTB domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
S100B S100 calcium binding protein B
S100P S100 calcium binding protein P
SLC38A2 solute carrier family 38, member 2
SMC4 structural maintenance of chromosomes 4
SOX10 SRY (sex determining region Y)-box 10
SULF1 sulfatase 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM100 transmembrane protein 100
TMEM2 transmembrane protein 2
TNS3 tensin 3
WNT5A wingless-type MMTV integration site family, member 5A
XYLT1 xylosyltransferase I