BRD-K13169950_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K13169950_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
BCL6 B-cell CLL/lymphoma 6
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRISP3 cysteine-rich secretory protein 3
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
ECM1 extracellular matrix protein 1
F13A1 coagulation factor XIII, A1 polypeptide
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GUSBP11 glucuronidase, beta pseudogene 11
HBB hemoglobin, beta
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HMOX1 heme oxygenase 1
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MPO myeloperoxidase
PLAUR plasminogen activator, urokinase receptor
POPDC3 popeye domain containing 3
RB1CC1 RB1-inducible coiled-coil 1
SLBP stem-loop binding protein
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
TUFT1 tuftelin 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
ASCL1 achaete-scute family bHLH transcription factor 1
AURKA aurora kinase A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CAPG capping protein (actin filament), gelsolin-like
CCNA2 cyclin A2
CCNF cyclin F
CDC25B cell division cycle 25B
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
CHMP4A charged multivesicular body protein 4A
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FAM13A family with sequence similarity 13, member A
GATA2 GATA binding protein 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
KIF20A kinesin family member 20A
LAMB1 laminin, beta 1
LGALS1 lectin, galactoside-binding, soluble, 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PRSS2 protease, serine, 2 (trypsin 2)
PSRC1 proline/serine-rich coiled-coil 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM47 RNA binding motif protein 47
RGS2 regulator of G-protein signaling 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SOX4 SRY (sex determining region Y)-box 4
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TRIB2 tribbles pseudokinase 2