BRD-K13049116_BMS-754807_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K13049116_BMS-754807_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADIPOQ adiponectin, C1Q and collagen domain containing
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DESI2 desumoylating isopeptidase 2
EHBP1L1 EH domain binding protein 1-like 1
G0S2 G0/G1 switch 2
GOLGA8A golgin A8 family, member A
H1F0 H1 histone family, member 0
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
JUND jun D proto-oncogene
KIAA0355 KIAA0355
KIF14 kinesin family member 14
KRAS Kirsten rat sarcoma viral oncogene homolog
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NT5E 5'-nucleotidase, ecto (CD73)
PDE8B phosphodiesterase 8B
PLIN1 perilipin 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RBPMS RNA binding protein with multiple splicing
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SRRM2 serine/arginine repetitive matrix 2
TBL1X transducin (beta)-like 1X-linked
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPBG trophoblast glycoprotein
TSPYL5 TSPY-like 5
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BLNK B-cell linker
CALD1 caldesmon 1
CCL2 chemokine (C-C motif) ligand 2
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CSRP2 cysteine and glycine-rich protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EPN2 epsin 2
FASTKD5 FAST kinase domains 5
FOSL1 FOS-like antigen 1
GADD45B growth arrest and DNA-damage-inducible, beta
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MFAP4 microfibrillar-associated protein 4
MOXD1 monooxygenase, DBH-like 1
NOP16 NOP16 nucleolar protein
NXN nucleoredoxin
PALLD palladin, cytoskeletal associated protein
PEA15 phosphoprotein enriched in astrocytes 15
PMM2 phosphomannomutase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RGS5 regulator of G-protein signaling 5
RPIA ribose 5-phosphate isomerase A
RPP40 ribonuclease P/MRP 40kDa subunit
S100A8 S100 calcium binding protein A8
SAMD4A sterile alpha motif domain containing 4A
SCG2 secretogranin II
SDC2 syndecan 2
SHB Src homology 2 domain containing adaptor protein B
SHROOM2 shroom family member 2
STAT1 signal transducer and activator of transcription 1, 91kDa
TFRC transferrin receptor