BRD-K12906962_DICHLOROBENZAMIL_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K12906962_DICHLOROBENZAMIL_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADCK3 aarF domain containing kinase 3
ALOX5 arachidonate 5-lipoxygenase
APOD apolipoprotein D
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTN3A3 butyrophilin, subfamily 3, member A3
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAV1 caveolin 1, caveolae protein, 22kDa
CCNG2 cyclin G2
CDO1 cysteine dioxygenase type 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL10 chemokine (C-X-C motif) ligand 10
CYB5R2 cytochrome b5 reductase 2
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FZD10 frizzled class receptor 10
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
HBB hemoglobin, beta
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
KIAA0226L KIAA0226-like
KLF11 Kruppel-like factor 11
LGALS8 lectin, galactoside-binding, soluble, 8
LY75 lymphocyte antigen 75
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MME membrane metallo-endopeptidase
MTSS1 metastasis suppressor 1
NEB nebulin
NUPR1 nuclear protein, transcriptional regulator, 1
OSBPL10 oxysterol binding protein-like 10
PDE4B phosphodiesterase 4B, cAMP-specific
PIKFYVE phosphoinositide kinase, FYVE finger containing
PTPRK protein tyrosine phosphatase, receptor type, K
PXDN peroxidasin
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
CCND1 cyclin D1
CDC42 cell division cycle 42
CSNK1A1 casein kinase 1, alpha 1
CTSC cathepsin C
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DEFB1 defensin, beta 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN1 endothelin 1
EGF epidermal growth factor
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
EIF5B eukaryotic translation initiation factor 5B
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GLIPR1 GLI pathogenesis-related 1
IGFBP3 insulin-like growth factor binding protein 3
KRT10 keratin 10, type I
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUP98 nucleoporin 98kDa
PON2 paraoxonase 2
PPIF peptidylprolyl isomerase F
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTRH2 peptidyl-tRNA hydrolase 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SLIRP SRA stem-loop interacting RNA binding protein
SRSF6 serine/arginine-rich splicing factor 6
THBS1 thrombospondin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
UBE2S ubiquitin-conjugating enzyme E2S
XIST X inactive specific transcript (non-protein coding)