BRD-K12906962_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K12906962_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAMBI BMP and activin membrane-bound inhibitor
CCL13 chemokine (C-C motif) ligand 13
CCNG2 cyclin G2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPYSL2 dihydropyrimidinase-like 2
FADS1 fatty acid desaturase 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GRB7 growth factor receptor-bound protein 7
HIST1H2BG histone cluster 1, H2bg
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
METTL7A methyltransferase like 7A
MTSS1 metastasis suppressor 1
NUPR1 nuclear protein, transcriptional regulator, 1
PHGDH phosphoglycerate dehydrogenase
QPRT quinolinate phosphoribosyltransferase
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SQLE squalene epoxidase
SQSTM1 sequestosome 1
SREBF2 sterol regulatory element binding transcription factor 2
STAG2 stromal antigen 2
TOB1 transducer of ERBB2, 1
TOX3 TOX high mobility group box family member 3
VEZF1 vascular endothelial zinc finger 1

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGRL2 adhesion G protein-coupled receptor L2
ALOX5 arachidonate 5-lipoxygenase
CDC25A cell division cycle 25A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLC Charcot-Leyden crystal galectin
CST7 cystatin F (leukocystatin)
DEFA4 defensin, alpha 4, corticostatin
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
GNAS GNAS complex locus
HBB hemoglobin, beta
IER3 immediate early response 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MPO myeloperoxidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEFH neurofilament, heavy polypeptide
NKX3-1 NK3 homeobox 1
NPY neuropeptide Y
ODC1 ornithine decarboxylase 1
PRR7 proline rich 7 (synaptic)
PTGIS prostaglandin I2 (prostacyclin) synthase
RPIA ribose 5-phosphate isomerase A
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STOM stomatin
TARP TCR gamma alternate reading frame protein
TNS1 tensin 1