BRD-K12762134_-666_MCF7_24.0_h_11.1_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K12762134_-666_MCF7_24.0_h_11.1_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAMBI BMP and activin membrane-bound inhibitor
CP ceruloplasmin (ferroxidase)
CPD carboxypeptidase D
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EPS8 epidermal growth factor receptor pathway substrate 8
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
KYNU kynureninase
LAMA3 laminin, alpha 3
MARCKSL1 MARCKS-like 1
MGP matrix Gla protein
NAMPT nicotinamide phosphoribosyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP1 nuclear receptor interacting protein 1
PDGFD platelet derived growth factor D
RAP1GAP RAP1 GTPase activating protein
SOX4 SRY (sex determining region Y)-box 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKT transketolase
TSC22D1 TSC22 domain family, member 1
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
VAT1 vesicle amine transport 1
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
DHRS2 dehydrogenase/reductase (SDR family) member 2
FHL2 four and a half LIM domains 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFITM3 interferon induced transmembrane protein 3
ODC1 ornithine decarboxylase 1
PGC progastricsin (pepsinogen C)
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
RGS4 regulator of G-protein signaling 4