BRD-K12539581_Nocodazole_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

103 genes differentially expressed following the BRD-K12539581_Nocodazole_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACTN1 actinin, alpha 1
CA12 carbonic anhydrase XII
CCND2 cyclin D2
CENPE centromere protein E, 312kDa
CNOT4 CCR4-NOT transcription complex, subunit 4
COBL cordon-bleu WH2 repeat protein
COL4A5 collagen, type IV, alpha 5
CREB3L2 cAMP responsive element binding protein 3-like 2
CRISP3 cysteine-rich secretory protein 3
CST1 cystatin SN
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELANE elastase, neutrophil expressed
FCGBP Fc fragment of IgG binding protein
GLIPR1 GLI pathogenesis-related 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HBB hemoglobin, beta
HBD hemoglobin, delta
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INSR insulin receptor
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
LEF1 lymphoid enhancer-binding factor 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP7 microtubule-associated protein 7
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NELL2 NEL-like 2 (chicken)
PDGFC platelet derived growth factor C
PDLIM5 PDZ and LIM domain 5
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGS1 regulator of G-protein signaling 1
RIN3 Ras and Rab interactor 3
SERINC5 serine incorporator 5
SFRP1 secreted frizzled-related protein 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
TPM1 tropomyosin 1 (alpha)
TPP1 tripeptidyl peptidase I
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARHGAP29 Rho GTPase activating protein 29
C3 complement component 3
CEP57 centrosomal protein 57kDa
CFI complement factor I
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
CP ceruloplasmin (ferroxidase)
DCN decorin
DLD dihydrolipoamide dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GPNMB glycoprotein (transmembrane) nmb
GSTA1 glutathione S-transferase alpha 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLTF helicase-like transcription factor
HOPX HOP homeobox
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP7 insulin-like growth factor binding protein 7
IL13RA2 interleukin 13 receptor, alpha 2
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC17 leucine rich repeat containing 17
MCM7 minichromosome maintenance complex component 7
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MME membrane metallo-endopeptidase
NREP neuronal regeneration related protein
PEG10 paternally expressed 10
PFN2 profilin 2
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLS3 plastin 3
S100A2 S100 calcium binding protein A2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGCE sarcoglycan, epsilon
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC38A1 solute carrier family 38, member 1
SMC1A structural maintenance of chromosomes 1A
SOX11 SRY (sex determining region Y)-box 11
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TAGLN2 transgelin 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A
TOP2A topoisomerase (DNA) II alpha 170kDa
TREM1 triggering receptor expressed on myeloid cells 1