BRD-K12502280_TG-101348_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K12502280_TG-101348_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMPH amphiphysin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
BIN1 bridging integrator 1
CELF2 CUGBP, Elav-like family member 2
DCLK1 doublecortin-like kinase 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EIF5A eukaryotic translation initiation factor 5A
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
KRT19 keratin 19, type I
MAMLD1 mastermind-like domain containing 1
MAP7 microtubule-associated protein 7
MAPT microtubule-associated protein tau
MBP myelin basic protein
PEG10 paternally expressed 10
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLXNC1 plexin C1
PON3 paraoxonase 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RTN1 reticulon 1
SCARB2 scavenger receptor class B, member 2
SEPP1 selenoprotein P, plasma, 1
SIK1 salt-inducible kinase 1
STMN2 stathmin 2
TSPAN13 tetraspanin 13
USP6NL USP6 N-terminal like
ZDHHC6 zinc finger, DHHC-type containing 6

decreased expression

Symbol Name
AIM1 absent in melanoma 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX5 arachidonate 5-lipoxygenase
CA12 carbonic anhydrase XII
CD200 CD200 molecule
CD24 CD24 molecule
CLEC5A C-type lectin domain family 5, member A
COCH cochlin
COL8A2 collagen, type VIII, alpha 2
CSRP2 cysteine and glycine-rich protein 2
DLD dihydrolipoamide dehydrogenase
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DPYD dihydropyrimidine dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR2 early growth response 2
F5 coagulation factor V (proaccelerin, labile factor)
FLT1 fms-related tyrosine kinase 1
FXYD2 FXYD domain containing ion transport regulator 2
GAL galanin/GMAP prepropeptide
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KRT15 keratin 15, type I
KYNU kynureninase
LEF1 lymphoid enhancer-binding factor 1
MAL mal, T-cell differentiation protein
MMP9 matrix metallopeptidase 9
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PODXL podocalyxin-like
RAB31 RAB31, member RAS oncogene family
REG1A regenerating islet-derived 1 alpha
RGCC regulator of cell cycle
S100A12 S100 calcium binding protein A12
SDC2 syndecan 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPP1 secreted phosphoprotein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRAPPC3 trafficking protein particle complex 3
VAV3 vav 3 guanine nucleotide exchange factor