BRD-K12502280_TG-101348_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K12502280_TG-101348_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOC aldolase C, fructose-bisphosphate
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CSTA cystatin A (stefin A)
CXCL13 chemokine (C-X-C motif) ligand 13
DSP desmoplakin
HIST2H2BE histone cluster 2, H2be
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
MATN2 matrilin 2
MYLK myosin light chain kinase
SCG5 secretogranin V
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATAD2 ATPase family, AAA domain containing 2
ATF5 activating transcription factor 5
CAPN1 calpain 1, (mu/I) large subunit
CCNE2 cyclin E2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL5A2 collagen, type V, alpha 2
COL6A2 collagen, type VI, alpha 2
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FHL1 four and a half LIM domains 1
FHL2 four and a half LIM domains 2
GBP2 guanylate binding protein 2, interferon-inducible
GNLY granulysin
GPR171 G protein-coupled receptor 171
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFI16 interferon, gamma-inducible protein 16
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LOXL1 lysyl oxidase-like 1
LY6E lymphocyte antigen 6 complex, locus E
PLTP phospholipid transfer protein
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLN sarcolipin
SNX10 sorting nexin 10
TFR2 transferrin receptor 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21