BRD-K12393722_1-benzhydryl-4-[(5-methyl-4-nitroisoxazol-3-yl)carbonyl]piperazine BRD-K12393722_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K12393722_1-benzhydryl-4-[(5-methyl-4-nitroisoxazol-3-yl)carbonyl]piperazine BRD-K12393722_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ARL4C ADP-ribosylation factor-like 4C
CA2 carbonic anhydrase II
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
CX3CR1 chemokine (C-X3-C motif) receptor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
EPAS1 endothelial PAS domain protein 1
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FOXF2 forkhead box F2
FXYD6 FXYD domain containing ion transport regulator 6
GAL galanin/GMAP prepropeptide
GPM6B glycoprotein M6B
HMOX1 heme oxygenase 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGKV4-1 immunoglobulin kappa variable 4-1
LAPTM4B lysosomal protein transmembrane 4 beta
MEIS2 Meis homeobox 2
MFAP2 microfibrillar-associated protein 2
MT1E metallothionein 1E
MX1 MX dynamin-like GTPase 1
NES nestin
PBX1 pre-B-cell leukemia homeobox 1
PDPN podoplanin
PROM1 prominin 1
PXDN peroxidasin
RBP1 retinol binding protein 1, cellular
RTN2 reticulon 2
SCG5 secretogranin V
SCGB2A1 secretoglobin, family 2A, member 1
SOX17 SRY (sex determining region Y)-box 17
SST somatostatin

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
C6ORF48 chromosome 6 open reading frame 48
CCL20 chemokine (C-C motif) ligand 20
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST3 cystatin C
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCK deoxycytidine kinase
DYNLT3 dynein, light chain, Tctex-type 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HACD2 3-hydroxyacyl-CoA dehydratase 2
HOXC6 homeobox C6
IFRD2 interferon-related developmental regulator 2
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
MGP matrix Gla protein
NKX3-1 NK3 homeobox 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
ODC1 ornithine decarboxylase 1
PRPF4 pre-mRNA processing factor 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCT glutaminyl-peptide cyclotransferase
SDC2 syndecan 2
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D4 TBC1 domain family, member 4
THAP11 THAP domain containing 11
TNC tenascin C
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5