BRD-K12184916_NVP-BEZ235_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K12184916_NVP-BEZ235_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APLP2 amyloid beta (A4) precursor-like protein 2
ATF3 activating transcription factor 3
CCL4 chemokine (C-C motif) ligand 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
CLDN10 claudin 10
DSP desmoplakin
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GLUL glutamate-ammonia ligase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP19 matrix metallopeptidase 19
MPZL2 myelin protein zero-like 2
PIP prolactin-induced protein
PLIN2 perilipin 2
RGS1 regulator of G-protein signaling 1
TACSTD2 tumor-associated calcium signal transducer 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ELP5 elongator acetyltransferase complex subunit 5
KLK10 kallikrein-related peptidase 10
KRT81 keratin 81, type II
MRPS2 mitochondrial ribosomal protein S2
MT1F metallothionein 1F
NT5E 5'-nucleotidase, ecto (CD73)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFF1 trefoil factor 1
TPBG trophoblast glycoprotein