BRD-K12120659_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K12120659_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
FSD1 fibronectin type III and SPRY domain containing 1
FST follistatin
GOLGA4 golgin A4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
L1CAM L1 cell adhesion molecule
LAMP5 lysosomal-associated membrane protein family, member 5
MX1 MX dynamin-like GTPase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
SCGB2A1 secretoglobin, family 2A, member 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TMSB15A thymosin beta 15a
TNNT1 troponin T type 1 (skeletal, slow)
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANXA1 annexin A1
BIK BCL2-interacting killer (apoptosis-inducing)
CXCL5 chemokine (C-X-C motif) ligand 5
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GSN gelsolin
KDM5D lysine (K)-specific demethylase 5D
KYNU kynureninase
LTBP1 latent transforming growth factor beta binding protein 1
MET MET proto-oncogene, receptor tyrosine kinase
MSMO1 methylsterol monooxygenase 1
PAIP1 poly(A) binding protein interacting protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SQLE squalene epoxidase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)