BRD-K12079898_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K12079898_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
ANPEP alanyl (membrane) aminopeptidase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CPA3 carboxypeptidase A3 (mast cell)
CRISP3 cysteine-rich secretory protein 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ELANE elastase, neutrophil expressed
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2BG histone cluster 1, H2bg
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HP haptoglobin
IL1R2 interleukin 1 receptor, type II
KDM5D lysine (K)-specific demethylase 5D
LBH limb bud and heart development
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
PRTN3 proteinase 3
RAP1GAP RAP1 GTPase activating protein
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPON2 spondin 2, extracellular matrix protein
SRGN serglycin
TRIB2 tribbles pseudokinase 2
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AGR2 anterior gradient 2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APOD apolipoprotein D
AREG amphiregulin
ARMCX2 armadillo repeat containing, X-linked 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD81 CD81 molecule
CHMP4A charged multivesicular body protein 4A
CIRBP cold inducible RNA binding protein
CXCL12 chemokine (C-X-C motif) ligand 12
DLD dihydrolipoamide dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM134B family with sequence similarity 134, member B
GPX3 glutathione peroxidase 3
HNMT histamine N-methyltransferase
IGL immunoglobulin lambda locus
ILK integrin-linked kinase
KRT14 keratin 14, type I
LAGE3 L antigen family, member 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MCAM melanoma cell adhesion molecule
MET MET proto-oncogene, receptor tyrosine kinase
MRPL19 mitochondrial ribosomal protein L19
NFIB nuclear factor I/B
PALLD palladin, cytoskeletal associated protein
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRSS23 protease, serine, 23
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCEA2 transcription elongation factor A (SII), 2
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN13 tetraspanin 13