BRD-K12040459_AT7867_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K12040459_AT7867_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ALDOA aldolase A, fructose-bisphosphate
CCL20 chemokine (C-C motif) ligand 20
COL5A2 collagen, type V, alpha 2
CSRP1 cysteine and glycine-rich protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FXYD3 FXYD domain containing ion transport regulator 3
GDF15 growth differentiation factor 15
GSN gelsolin
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IPO13 importin 13
KDM5D lysine (K)-specific demethylase 5D
KRT23 keratin 23, type I
MME membrane metallo-endopeptidase
MX2 MX dynamin-like GTPase 2
MYO6 myosin VI
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPIC peptidylprolyl isomerase C (cyclophilin C)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTX3 pentraxin 3, long
QPCT glutaminyl-peptide cyclotransferase
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A4 S100 calcium binding protein A4
SOBP sine oculis binding protein homolog (Drosophila)
SPINK1 serine peptidase inhibitor, Kazal type 1
TGFBR3 transforming growth factor, beta receptor III
TMEM2 transmembrane protein 2
TST thiosulfate sulfurtransferase (rhodanese)
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
VDAC1 voltage-dependent anion channel 1
WDR61 WD repeat domain 61

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
C8ORF4 chromosome 8 open reading frame 4
CCL19 chemokine (C-C motif) ligand 19
CLU clusterin
CORO1A coronin, actin binding protein, 1A
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL13 chemokine (C-X-C motif) ligand 13
EIF5A eukaryotic translation initiation factor 5A
EPHA3 EPH receptor A3
FGFR2 fibroblast growth factor receptor 2
FOLR1 folate receptor 1 (adult)
GRWD1 glutamate-rich WD repeat containing 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP7 insulin-like growth factor binding protein 7
KIF14 kinesin family member 14
KRT7 keratin 7, type II
LAMC2 laminin, gamma 2
LTF lactotransferrin
MATN2 matrilin 2
MSN moesin
PIP prolactin-induced protein
PLAC8 placenta-specific 8
PODXL podocalyxin-like
PRR15L proline rich 15-like
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SMC1A structural maintenance of chromosomes 1A
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
TEX10 testis expressed 10
TFF1 trefoil factor 1
TTK TTK protein kinase
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)