BRD-K11911061_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K11911061_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
AKAP12 A kinase (PRKA) anchor protein 12
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD163 CD163 molecule
CFB complement factor B
CRIP1 cysteine-rich protein 1 (intestinal)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCLK1 doublecortin-like kinase 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP4 dual specificity phosphatase 4
F13A1 coagulation factor XIII, A1 polypeptide
GAS1 growth arrest-specific 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
INSIG1 insulin induced gene 1
KRT7 keratin 7, type II
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
PDE4B phosphodiesterase 4B, cAMP-specific
PNMA2 paraneoplastic Ma antigen 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SYT1 synaptotagmin I
THBS1 thrombospondin 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPBG trophoblast glycoprotein
TRIB3 tribbles pseudokinase 3
VCAN versican
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
BTG3 BTG family, member 3
EMP2 epithelial membrane protein 2
GJA1 gap junction protein, alpha 1, 43kDa
KLK11 kallikrein-related peptidase 11
LYPD1 LY6/PLAUR domain containing 1
MRPL19 mitochondrial ribosomal protein L19
NQO1 NAD(P)H dehydrogenase, quinone 1
PIR pirin (iron-binding nuclear protein)
PLS3 plastin 3
SDC2 syndecan 2
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TRA2A transformer 2 alpha homolog (Drosophila)
TXNDC9 thioredoxin domain containing 9
VAMP8 vesicle-associated membrane protein 8
WNT5A wingless-type MMTV integration site family, member 5A