BRD-K11911061_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K11911061_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ANXA6 annexin A6
BTG1 B-cell translocation gene 1, anti-proliferative
CST1 cystatin SN
DDIT4 DNA-damage-inducible transcript 4
F13A1 coagulation factor XIII, A1 polypeptide
FOXO3 forkhead box O3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MSRA methionine sulfoxide reductase A
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PHGDH phosphoglycerate dehydrogenase
S100A11 S100 calcium binding protein A11
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SOX4 SRY (sex determining region Y)-box 4
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
TKT transketolase

decreased expression

Symbol Name
CCNB1 cyclin B1
CLCA1 chloride channel accessory 1
CLCA4 chloride channel accessory 4
CXCL9 chemokine (C-X-C motif) ligand 9
DEFA5 defensin, alpha 5, Paneth cell-specific
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHRS9 dehydrogenase/reductase (SDR family) member 9
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRZB frizzled-related protein
GATA2 GATA binding protein 2
GNAS GNAS complex locus
NEFH neurofilament, heavy polypeptide
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
OLFM4 olfactomedin 4
PEG10 paternally expressed 10
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SNAI2 snail family zinc finger 2
SPARCL1 SPARC-like 1 (hevin)
TGM2 transglutaminase 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TUBB2A tubulin, beta 2A class IIa
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
ZNF512B zinc finger protein 512B