BRD-K11696279_BU 239 hydrochloride_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

152 genes differentially expressed following the BRD-K11696279_BU 239 hydrochloride_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT1 acetyl-CoA acetyltransferase 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADGRG6 adhesion G protein-coupled receptor G6
AREG amphiregulin
ASS1 argininosuccinate synthase 1
BIRC3 baculoviral IAP repeat containing 3
C3 complement component 3
CCL20 chemokine (C-C motif) ligand 20
CD47 CD47 molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFB complement factor B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTSD cathepsin D
CXCL2 chemokine (C-X-C motif) ligand 2
CYB5A cytochrome b5 type A (microsomal)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FKBP5 FK506 binding protein 5
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
HBB hemoglobin, beta
JADE2 jade family PHD finger 2
KLF6 Kruppel-like factor 6
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MCL1 myeloid cell leukemia 1
MME membrane metallo-endopeptidase
MUC1 mucin 1, cell surface associated
NNMT nicotinamide N-methyltransferase
OLFM4 olfactomedin 4
ORM1 orosomucoid 1
PDZK1IP1 PDZK1 interacting protein 1
PER1 period circadian clock 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRUNE2 prune homolog 2 (Drosophila)
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFTPB surfactant protein B
SFTPC surfactant protein C
SIK1 salt-inducible kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOD2 superoxide dismutase 2, mitochondrial
SPINK1 serine peptidase inhibitor, Kazal type 1
SQRDL sulfide quinone reductase-like (yeast)
STOM stomatin
TATDN2 TatD DNase domain containing 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC22D3 TSC22 domain family, member 3
VNN1 vanin 1
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANO1 anoctamin 1, calcium activated chloride channel
ANOS1 anosmin 1
ARL4C ADP-ribosylation factor-like 4C
ASCL1 achaete-scute family bHLH transcription factor 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BMP2 bone morphogenetic protein 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCL2 chemokine (C-C motif) ligand 2
CCNF cyclin F
CNN3 calponin 3, acidic
COL13A1 collagen, type XIII, alpha 1
COL15A1 collagen, type XV, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CREB3L1 cAMP responsive element binding protein 3-like 1
CST1 cystatin SN
CST4 cystatin S
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTNND1 catenin (cadherin-associated protein), delta 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DIO2 deiodinase, iodothyronine, type II
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNM1 dynamin 1
DST dystonin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP4 dual specificity phosphatase 4
EPHB2 EPH receptor B2
ETV1 ets variant 1
ETV5 ets variant 5
F3 coagulation factor III (thromboplastin, tissue factor)
FADS1 fatty acid desaturase 1
FAM129A family with sequence similarity 129, member A
FGFR1 fibroblast growth factor receptor 1
FHL2 four and a half LIM domains 2
FMOD fibromodulin
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
FZD10 frizzled class receptor 10
FZD2 frizzled class receptor 2
FZD7 frizzled class receptor 7
GEM GTP binding protein overexpressed in skeletal muscle
GJA1 gap junction protein, alpha 1, 43kDa
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GTSE1 G-2 and S-phase expressed 1
H1F0 H1 histone family, member 0
HES1 hes family bHLH transcription factor 1
HJURP Holliday junction recognition protein
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
KIF14 kinesin family member 14
KRT1 keratin 1, type II
LAMA4 laminin, alpha 4
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LIF leukemia inhibitory factor
MAP1B microtubule-associated protein 1B
MATN2 matrilin 2
MMP12 matrix metallopeptidase 12
NEK2 NIMA-related kinase 2
NGRN neugrin, neurite outgrowth associated
NKX3-1 NK3 homeobox 1
PBX3 pre-B-cell leukemia homeobox 3
PDGFA platelet-derived growth factor alpha polypeptide
PLK2 polo-like kinase 2
PRC1 protein regulator of cytokinesis 1
PTN pleiotrophin
RAP1GAP RAP1 GTPase activating protein
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
S100A2 S100 calcium binding protein A2
SCG5 secretogranin V
SDC2 syndecan 2
SFRP1 secreted frizzled-related protein 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPDEF SAM pointed domain containing ETS transcription factor
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPRR1A small proline-rich protein 1A
SPRY2 sprouty homolog 2 (Drosophila)
STC1 stanniocalcin 1
SYNJ2 synaptojanin 2
TBX3 T-box 3
TFF3 trefoil factor 3 (intestinal)
TGFBI transforming growth factor, beta-induced, 68kDa
THBD thrombomodulin
TNC tenascin C
TPM1 tropomyosin 1 (alpha)
UBE2S ubiquitin-conjugating enzyme E2S
WIF1 WNT inhibitory factor 1
WSB2 WD repeat and SOCS box containing 2