BRD-K11663430_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

175 genes differentially expressed following the BRD-K11663430_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACOT13 acyl-CoA thioesterase 13
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALOX5 arachidonate 5-lipoxygenase
ANKRD46 ankyrin repeat domain 46
ARHGAP29 Rho GTPase activating protein 29
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPN asporin
BZW2 basic leucine zipper and W2 domains 2
C3 complement component 3
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL20 chemokine (C-C motif) ligand 20
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCA1 chloride channel accessory 1
COL15A1 collagen, type XV, alpha 1
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
CPD carboxypeptidase D
CPE carboxypeptidase E
CXADR coxsackie virus and adenovirus receptor
CYB5A cytochrome b5 type A (microsomal)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENAH enabled homolog (Drosophila)
EPAS1 endothelial PAS domain protein 1
FABP1 fatty acid binding protein 1, liver
FRY furry homolog (Drosophila)
GAGE3 G antigen 3
GLRX glutaredoxin (thioltransferase)
GREM1 gremlin 1, DAN family BMP antagonist
HEBP1 heme binding protein 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IPO13 importin 13
KCTD12 potassium channel tetramerization domain containing 12
LMO3 LIM domain only 3 (rhombotin-like 2)
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
METRN meteorin, glial cell differentiation regulator
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
MTFR1 mitochondrial fission regulator 1
MTSS1 metastasis suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NRGN neurogranin (protein kinase C substrate, RC3)
OPN3 opsin 3
ORM1 orosomucoid 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PEX11A peroxisomal biogenesis factor 11 alpha
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PPAP2A phosphatidic acid phosphatase type 2A
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRR15L proline rich 15-like
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTK2 protein tyrosine kinase 2
RAB40B RAB40B, member RAS oncogene family
RAD51C RAD51 paralog C
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REG3A regenerating islet-derived 3 alpha
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
RHOB ras homolog family member B
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SCPEP1 serine carboxypeptidase 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SNAP29 synaptosomal-associated protein, 29kDa
SPINK1 serine peptidase inhibitor, Kazal type 1
SYBU syntabulin (syntaxin-interacting)
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TKTL1 transketolase-like 1
TMEM30B transmembrane protein 30B
TPSAB1 tryptase alpha/beta 1
TRIM2 tripartite motif containing 2
TSPAN7 tetraspanin 7
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AK4 adenylate kinase 4
ATF1 activating transcription factor 1
AURKA aurora kinase A
BST2 bone marrow stromal cell antigen 2
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CDC42 cell division cycle 42
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CRYAB crystallin, alpha B
CTBP1 C-terminal binding protein 1
CTSZ cathepsin Z
CXCL3 chemokine (C-X-C motif) ligand 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DUT deoxyuridine triphosphatase
EFS embryonal Fyn-associated substrate
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
GABPB1 GA binding protein transcription factor, beta subunit 1
HAS2 hyaluronan synthase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSPA8 heat shock 70kDa protein 8
IRAK1 interleukin-1 receptor-associated kinase 1
JADE2 jade family PHD finger 2
KDM5D lysine (K)-specific demethylase 5D
KLK11 kallikrein-related peptidase 11
KRT10 keratin 10, type I
KRT14 keratin 14, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNB1 lamin B1
LOX lysyl oxidase
LY6D lymphocyte antigen 6 complex, locus D
MAPK6 mitogen-activated protein kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MGLL monoglyceride lipase
MRPL23 mitochondrial ribosomal protein L23
MSX1 msh homeobox 1
MTA1 metastasis associated 1
NBN nibrin
NCOR2 nuclear receptor corepressor 2
NES nestin
NKX3-1 NK3 homeobox 1
NPEPL1 aminopeptidase-like 1
NUP62 nucleoporin 62kDa
PARP2 poly (ADP-ribose) polymerase 2
PDLIM1 PDZ and LIM domain 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PODXL podocalyxin-like
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTX3 pentraxin 3, long
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SLC25A46 solute carrier family 25, member 46
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLPI secretory leukocyte peptidase inhibitor
SORBS3 sorbin and SH3 domain containing 3
SPATA20 spermatogenesis associated 20
STXBP2 syntaxin binding protein 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TRIM44 tripartite motif containing 44
TRIP6 thyroid hormone receptor interactor 6
TSKU tsukushi, small leucine rich proteoglycan
TYRP1 tyrosinase-related protein 1
XBP1 X-box binding protein 1
ZNF586 zinc finger protein 586