BRD-K11558771_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K11558771_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
APLP2 amyloid beta (A4) precursor-like protein 2
BEX4 brain expressed, X-linked 4
C10ORF10 chromosome 10 open reading frame 10
CD52 CD52 molecule
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
EGR2 early growth response 2
F13A1 coagulation factor XIII, A1 polypeptide
FABP7 fatty acid binding protein 7, brain
FCGBP Fc fragment of IgG binding protein
GNAS GNAS complex locus
HMOX1 heme oxygenase 1
LPAR6 lysophosphatidic acid receptor 6
MDK midkine (neurite growth-promoting factor 2)
PEG10 paternally expressed 10
PEG3 paternally expressed 3
RUNX1 runt-related transcription factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TMSB15A thymosin beta 15a
ZNF415 zinc finger protein 415
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
CDC42 cell division cycle 42
CEP55 centrosomal protein 55kDa
CKS2 CDC28 protein kinase regulatory subunit 2
EIF5A eukaryotic translation initiation factor 5A
KANK1 KN motif and ankyrin repeat domains 1
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
MAP7 microtubule-associated protein 7
MT1E metallothionein 1E
S100A1 S100 calcium binding protein A1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3