BRD-K11267252_CH5424802_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K11267252_CH5424802_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AUTS2 autism susceptibility candidate 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CECR5 cat eye syndrome chromosome region, candidate 5
COG7 component of oligomeric golgi complex 7
CRABP1 cellular retinoic acid binding protein 1
EPHB2 EPH receptor B2
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GRAMD4 GRAM domain containing 4
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
MAGEA12 melanoma antigen family A12
MMP12 matrix metallopeptidase 12
NPIPB3 nuclear pore complex interacting protein family, member B3
PLS1 plastin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SFRP1 secreted frizzled-related protein 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STC1 stanniocalcin 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD28 ankyrin repeat domain 28
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
CYB5A cytochrome b5 type A (microsomal)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DPT dermatopontin
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
GPM6B glycoprotein M6B
GULP1 GULP, engulfment adaptor PTB domain containing 1
KDM5D lysine (K)-specific demethylase 5D
LRRC17 leucine rich repeat containing 17
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NDNF neuron-derived neurotrophic factor
NNMT nicotinamide N-methyltransferase
OLFM1 olfactomedin 1
PFN2 profilin 2
RPL31 ribosomal protein L31
RPS5 ribosomal protein S5
SEPP1 selenoprotein P, plasma, 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TXNDC9 thioredoxin domain containing 9
UBE2E1 ubiquitin-conjugating enzyme E2E 1
VCAM1 vascular cell adhesion molecule 1
YME1L1 YME1-like 1 ATPase