BRD-K11072542_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K11072542_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ALB albumin
APOLD1 apolipoprotein L domain containing 1
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CFD complement factor D (adipsin)
CLC Charcot-Leyden crystal galectin
CPA3 carboxypeptidase A3 (mast cell)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYR61 cysteine-rich, angiogenic inducer, 61
DMXL2 Dmx-like 2
FOSL1 FOS-like antigen 1
FST follistatin
GADD45A growth arrest and DNA-damage-inducible, alpha
GLIPR1 GLI pathogenesis-related 1
HIC2 hypermethylated in cancer 2
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
HIST2H2BE histone cluster 2, H2be
IGHM immunoglobulin heavy constant mu
JAG1 jagged 1
LEF1 lymphoid enhancer-binding factor 1
LGALS4 lectin, galactoside-binding, soluble, 4
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NELL2 NEL-like 2 (chicken)
OLFM4 olfactomedin 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TCL1A T-cell leukemia/lymphoma 1A
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPM1 tropomyosin 1 (alpha)
TRIB2 tribbles pseudokinase 2
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ATP9A ATPase, class II, type 9A
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C8ORF4 chromosome 8 open reading frame 4
CD47 CD47 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CYB5A cytochrome b5 type A (microsomal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
FAM57A family with sequence similarity 57, member A
GATA3 GATA binding protein 3
HILPDA hypoxia inducible lipid droplet-associated
IFITM1 interferon induced transmembrane protein 1
IGFBP4 insulin-like growth factor binding protein 4
MELK maternal embryonic leucine zipper kinase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NET1 neuroepithelial cell transforming 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH2 notch 2
OLFML3 olfactomedin-like 3
OXA1L oxidase (cytochrome c) assembly 1-like
PTGES prostaglandin E synthase
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RFC2 replication factor C (activator 1) 2, 40kDa
STAT1 signal transducer and activator of transcription 1, 91kDa
TACSTD2 tumor-associated calcium signal transducer 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM97 transmembrane protein 97
TOP2A topoisomerase (DNA) II alpha 170kDa
TRAM1 translocation associated membrane protein 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGCG UDP-glucose ceramide glucosyltransferase
WFDC2 WAP four-disulfide core domain 2
XBP1 X-box binding protein 1