BRD-K10870738_CDC_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K10870738_CDC_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKR1C3 aldo-keto reductase family 1, member C3
ASS1 argininosuccinate synthase 1
BLVRB biliverdin reductase B
C8ORF4 chromosome 8 open reading frame 4
CD40 CD40 molecule, TNF receptor superfamily member 5
CHGB chromogranin B
CLPTM1 cleft lip and palate associated transmembrane protein 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRISP3 cysteine-rich secretory protein 3
CXCL10 chemokine (C-X-C motif) ligand 10
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
E2F2 E2F transcription factor 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
HMOX1 heme oxygenase 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KYNU kynureninase
MARS methionyl-tRNA synthetase
MCOLN1 mucolipin 1
OLFM1 olfactomedin 1
PDIA3 protein disulfide isomerase family A, member 3
PEX11A peroxisomal biogenesis factor 11 alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
QPCT glutaminyl-peptide cyclotransferase
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC38A1 solute carrier family 38, member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SNAP25 synaptosomal-associated protein, 25kDa
TMEM176B transmembrane protein 176B
TMSB15A thymosin beta 15a
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
AIM1 absent in melanoma 1
CCL2 chemokine (C-C motif) ligand 2
CHRDL1 chordin-like 1
CNN3 calponin 3, acidic
COL1A1 collagen, type I, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DHCR24 24-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
FABP4 fatty acid binding protein 4, adipocyte
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HAS2 hyaluronan synthase 2
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HOXA5 homeobox A5
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOX lysyl oxidase
LRRC17 leucine rich repeat containing 17
MSMO1 methylsterol monooxygenase 1
PDGFC platelet derived growth factor C
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PLAU plasminogen activator, urokinase
PTX3 pentraxin 3, long
PUF60 poly-U binding splicing factor 60KDa
RBM47 RNA binding motif protein 47
RPA3 replication protein A3, 14kDa
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SGCE sarcoglycan, epsilon
SLIT2 slit homolog 2 (Drosophila)
SNRPE small nuclear ribonucleoprotein polypeptide E
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPON1 spondin 1, extracellular matrix protein
SRPX sushi-repeat containing protein, X-linked
TACSTD2 tumor-associated calcium signal transducer 2
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNC tenascin C
VCAN versican