BRD-K10010115_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K10010115_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ADIRF adipogenesis regulatory factor
ANXA4 annexin A4
ARL4C ADP-ribosylation factor-like 4C
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CKB creatine kinase, brain
CTGF connective tissue growth factor
DNTT DNA nucleotidylexotransferase
EDNRA endothelin receptor type A
EGLN3 egl-9 family hypoxia-inducible factor 3
EPAS1 endothelial PAS domain protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FHL1 four and a half LIM domains 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
MMD monocyte to macrophage differentiation-associated
NLRP2 NLR family, pyrin domain containing 2
OLFM4 olfactomedin 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STON1 stonin 1
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17

decreased expression

Symbol Name
CKAP4 cytoskeleton-associated protein 4
CTR9 CTR9, Paf1/RNA polymerase II complex component
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
GTPBP8 GTP-binding protein 8 (putative)
MRPS30 mitochondrial ribosomal protein S30
RRM1 ribonucleotide reductase M1
SPRR3 small proline-rich protein 3