BRD-K10010115_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K10010115_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
BTG1 B-cell translocation gene 1, anti-proliferative
BZW2 basic leucine zipper and W2 domains 2
C10ORF10 chromosome 10 open reading frame 10
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD2 CD2 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD53 CD53 molecule
CFD complement factor D (adipsin)
CHIC2 cysteine-rich hydrophobic domain 2
CHRDL1 chordin-like 1
CLC Charcot-Leyden crystal galectin
COLEC12 collectin sub-family member 12
CPA3 carboxypeptidase A3 (mast cell)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DGKA diacylglycerol kinase, alpha 80kDa
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP5 dual specificity phosphatase 5
EIF5A eukaryotic translation initiation factor 5A
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM63A family with sequence similarity 63, member A
FAM65B family with sequence similarity 65, member B
FBP1 fructose-1,6-bisphosphatase 1
FHL1 four and a half LIM domains 1
FKBP11 FK506 binding protein 11, 19 kDa
FOXO1 forkhead box O1
FYB FYN binding protein
G0S2 G0/G1 switch 2
GIMAP4 GTPase, IMAP family member 4
GLRX glutaredoxin (thioltransferase)
GNLY granulysin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INHBA inhibin, beta A
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAG1 jagged 1
KIAA0226L KIAA0226-like
KRT18 keratin 18, type I
LAMB1 laminin, beta 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LXN latexin
LYZ lysozyme
MTSS1 metastasis suppressor 1
MZB1 marginal zone B and B1 cell-specific protein
NT5E 5'-nucleotidase, ecto (CD73)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PCCA propionyl CoA carboxylase, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
S100A10 S100 calcium binding protein A10
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPX sushi-repeat containing protein, X-linked
STON1 stonin 1
SULF1 sulfatase 1
SYNGR3 synaptogyrin 3
TARP TCR gamma alternate reading frame protein
TFPI2 tissue factor pathway inhibitor 2
TRD T cell receptor delta locus
TXNIP thioredoxin interacting protein
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CDC42 cell division cycle 42
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CLIC4 chloride intracellular channel 4
CPB1 carboxypeptidase B1 (tissue)
EMX2 empty spiracles homeobox 2
FAM46A family with sequence similarity 46, member A
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GRIA2 glutamate receptor, ionotropic, AMPA 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MMP10 matrix metallopeptidase 10
MUC16 mucin 16, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
PCSK1 proprotein convertase subtilisin/kexin type 1
PEA15 phosphoprotein enriched in astrocytes 15
PIP prolactin-induced protein
PODXL podocalyxin-like
QPRT quinolinate phosphoribosyltransferase
SCGB2A1 secretoglobin, family 2A, member 1
SUB1 SUB1 homolog (S. cerevisiae)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TPBG trophoblast glycoprotein
TPM4 tropomyosin 4