BRD-K09991945_GSK-3 Inhibitor II_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K09991945_GSK-3 Inhibitor II_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA3 annexin A3
ASNS asparagine synthetase (glutamine-hydrolyzing)
CA12 carbonic anhydrase XII
CALB1 calbindin 1, 28kDa
CALD1 caldesmon 1
CD24 CD24 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FMOD fibromodulin
FN1 fibronectin 1
FXYD3 FXYD domain containing ion transport regulator 3
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INHBA inhibin, beta A
LYZ lysozyme
MFAP5 microfibrillar associated protein 5
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TIMP3 TIMP metallopeptidase inhibitor 3
TRIB3 tribbles pseudokinase 3
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
CXCL13 chemokine (C-X-C motif) ligand 13
DHRS2 dehydrogenase/reductase (SDR family) member 2
MMP1 matrix metallopeptidase 1
PDZK1IP1 PDZK1 interacting protein 1
PLK2 polo-like kinase 2
PTN pleiotrophin
RGS1 regulator of G-protein signaling 1
RTN2 reticulon 2
SHOX2 short stature homeobox 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2