BRD-K09991945_GSK-3 Inhibitor II_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K09991945_GSK-3 Inhibitor II_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
CAST calpastatin
DDIT4 DNA-damage-inducible transcript 4
FRZB frizzled-related protein
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
NPTX2 neuronal pentraxin II
PHGDH phosphoglycerate dehydrogenase
SLC38A1 solute carrier family 38, member 1
TGFBI transforming growth factor, beta-induced, 68kDa
THBS2 thrombospondin 2
TOB1 transducer of ERBB2, 1

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
COL4A5 collagen, type IV, alpha 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
GNAS GNAS complex locus
KLK11 kallikrein-related peptidase 11
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NTS neurotensin
PRAME preferentially expressed antigen in melanoma