BRD-K09854848_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K09854848_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOC1 apolipoprotein C-I
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
CD99 CD99 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPU centromere protein U
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNN3 calponin 3, acidic
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
FILIP1L filamin A interacting protein 1-like
GADD45B growth arrest and DNA-damage-inducible, beta
HBB hemoglobin, beta
HIST1H2AE histone cluster 1, H2ae
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
HYOU1 hypoxia up-regulated 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5 immediate early response 5
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KIAA0226L KIAA0226-like
KLF6 Kruppel-like factor 6
LAPTM5 lysosomal protein transmembrane 5
LOC100505650 uncharacterized LOC100505650
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRCAM neuronal cell adhesion molecule
NUPR1 nuclear protein, transcriptional regulator, 1
PCDH9 protocadherin 9
PDE4B phosphodiesterase 4B, cAMP-specific
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PON3 paraoxonase 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGS1 regulator of G-protein signaling 1
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SPARCL1 SPARC-like 1 (hevin)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TXNL4B thioredoxin-like 4B
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
B3GNT1
BASP1 brain abundant, membrane attached signal protein 1
BLCAP bladder cancer associated protein
BST2 bone marrow stromal cell antigen 2
BTBD3 BTB (POZ) domain containing 3
CCNB1 cyclin B1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSTA cystatin A (stefin A)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
EMG1 EMG1 N1-specific pseudouridine methyltransferase
FKBP1B FK506 binding protein 1B, 12.6 kDa
HCP5 HLA complex P5 (non-protein coding)
HOXA5 homeobox A5
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KRT18 keratin 18, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LBR lamin B receptor
MARCKS myristoylated alanine-rich protein kinase C substrate
MME membrane metallo-endopeptidase
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRIP1 nuclear receptor interacting protein 1
PCNA proliferating cell nuclear antigen
PEG10 paternally expressed 10
PFN2 profilin 2
PGAM1 phosphoglycerate mutase 1 (brain)
PTX3 pentraxin 3, long
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
TNS3 tensin 3
ZBED5 zinc finger, BED-type containing 5