BRD-K09778810_FGIN-1-27_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K09778810_FGIN-1-27_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BSG basigin (Ok blood group)
CA2 carbonic anhydrase II
CCL5 chemokine (C-C motif) ligand 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK14 cyclin-dependent kinase 14
CHN1 chimerin 1
CKB creatine kinase, brain
CLPTM1 cleft lip and palate associated transmembrane protein 1
COL15A1 collagen, type XV, alpha 1
COL5A1 collagen, type V, alpha 1
COPA coatomer protein complex, subunit alpha
CST7 cystatin F (leukocystatin)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CYB561 cytochrome b561
EPAS1 endothelial PAS domain protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EZR ezrin
G6PD glucose-6-phosphate dehydrogenase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GCLC glutamate-cysteine ligase, catalytic subunit
GPATCH8 G patch domain containing 8
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPG2 heparan sulfate proteoglycan 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITGA6 integrin, alpha 6
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KRT13 keratin 13, type I
LAMP1 lysosomal-associated membrane protein 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MSMB microseminoprotein, beta-
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUCB1 nucleobindin 1
PBX1 pre-B-cell leukemia homeobox 1
PLD3 phospholipase D family, member 3
PLEC plectin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX11 SRY (sex determining region Y)-box 11
STAB1 stabilin 1
TFEC transcription factor EC
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TLN1 talin 1
UPK1B uroplakin 1B
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BACE2 beta-site APP-cleaving enzyme 2
CELF2 CUGBP, Elav-like family member 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHSY1 chondroitin sulfate synthase 1
CLTB clathrin, light chain B
COL14A1 collagen, type XIV, alpha 1
COMMD8 COMM domain containing 8
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DCT dopachrome tautomerase
DPEP1 dipeptidase 1 (renal)
EPHA3 EPH receptor A3
FRZB frizzled-related protein
GSTM3 glutathione S-transferase mu 3 (brain)
HEBP1 heme binding protein 1
HOXC6 homeobox C6
ICAM2 intercellular adhesion molecule 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MATN2 matrilin 2
MGP matrix Gla protein
MINA MYC induced nuclear antigen
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
NPY1R neuropeptide Y receptor Y1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
RPP25 ribonuclease P/MRP 25kDa subunit
SPINK1 serine peptidase inhibitor, Kazal type 1
SYBU syntabulin (syntaxin-interacting)
TMEM45A transmembrane protein 45A
TXNDC9 thioredoxin domain containing 9
TYRP1 tyrosinase-related protein 1
ZNF721 zinc finger protein 721