BRD-K09638361_IC 261_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-K09638361_IC 261_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
AIM1 absent in melanoma 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA10 annexin A10
ANXA6 annexin A6
ARG2 arginase 2
AURKA aurora kinase A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CD24 CD24 molecule
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
DDIT3 DNA-damage-inducible transcript 3
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FHOD3 formin homology 2 domain containing 3
FOSL1 FOS-like antigen 1
GLIPR1 GLI pathogenesis-related 1
H2AFV H2A histone family, member V
HBEGF heparin-binding EGF-like growth factor
HIST1H1C histone cluster 1, H1c
HSPB8 heat shock 22kDa protein 8
IFI16 interferon, gamma-inducible protein 16
ILK integrin-linked kinase
IRF8 interferon regulatory factor 8
ITGA6 integrin, alpha 6
KLK3 kallikrein-related peptidase 3
LDLR low density lipoprotein receptor
LMO4 LIM domain only 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MIR22HG MIR22 host gene
MX1 MX dynamin-like GTPase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NDC80 NDC80 kinetochore complex component
NEFH neurofilament, heavy polypeptide
NKX3-1 NK3 homeobox 1
NMT2 N-myristoyltransferase 2
NTAN1 N-terminal asparagine amidase
PDIA3 protein disulfide isomerase family A, member 3
PEA15 phosphoprotein enriched in astrocytes 15
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PSRC1 proline/serine-rich coiled-coil 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRF protein tyrosine phosphatase, receptor type, F
PTX3 pentraxin 3, long
RGCC regulator of cell cycle
RIMS3 regulating synaptic membrane exocytosis 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SCPEP1 serine carboxypeptidase 1
STAR steroidogenic acute regulatory protein
STC2 stanniocalcin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM35 transmembrane protein 35
TRAPPC3 trafficking protein particle complex 3
TXNIP thioredoxin interacting protein
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
BZW2 basic leucine zipper and W2 domains 2
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CFI complement factor I
CLNS1A chloride channel, nucleotide-sensitive, 1A
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL5 chemokine (C-X-C motif) ligand 5
DDAH1 dimethylarginine dimethylaminohydrolase 1
EPN2 epsin 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFR3 fibroblast growth factor receptor 3
GLUL glutamate-ammonia ligase
GMDS GDP-mannose 4,6-dehydratase
GRIA2 glutamate receptor, ionotropic, AMPA 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IRX5 iroquois homeobox 5
KIAA0101 KIAA0101
LAPTM4B lysosomal protein transmembrane 4 beta
LMCD1 LIM and cysteine-rich domains 1
LRRC16A leucine rich repeat containing 16A
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
MDFIC MyoD family inhibitor domain containing
MMP12 matrix metallopeptidase 12
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5C myosin VC
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDS5A PDS5 cohesin associated factor A
PLS1 plastin 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PTPRD protein tyrosine phosphatase, receptor type, D
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TESC tescalcin
TFF3 trefoil factor 3 (intestinal)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNC tenascin C
TSPAN8 tetraspanin 8
VAV3 vav 3 guanine nucleotide exchange factor
WLS wntless Wnt ligand secretion mediator