BRD-K09638361_IC 261_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K09638361_IC 261_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ARHGAP29 Rho GTPase activating protein 29
CAV1 caveolin 1, caveolae protein, 22kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
EDN1 endothelin 1
ENAH enabled homolog (Drosophila)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GBP1 guanylate binding protein 1, interferon-inducible
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDAC9 histone deacetylase 9
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KLF4 Kruppel-like factor 4 (gut)
NELL2 NEL-like 2 (chicken)
NGRN neugrin, neurite outgrowth associated
NRN1 neuritin 1
ODC1 ornithine decarboxylase 1
PCLO piccolo presynaptic cytomatrix protein
PGC progastricsin (pepsinogen C)
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PTPRK protein tyrosine phosphatase, receptor type, K
RGCC regulator of cell cycle
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOX11 SRY (sex determining region Y)-box 11
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TRDV3 T cell receptor delta variable 3
TUBB2A tubulin, beta 2A class IIa
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
ZFP36 ZFP36 ring finger protein
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADD3 adducin 3 (gamma)
APOD apolipoprotein D
BDH2 3-hydroxybutyrate dehydrogenase, type 2
C6ORF48 chromosome 6 open reading frame 48
C9ORF3 chromosome 9 open reading frame 3
CCNE2 cyclin E2
COL11A1 collagen, type XI, alpha 1
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
CXCL12 chemokine (C-X-C motif) ligand 12
F13A1 coagulation factor XIII, A1 polypeptide
GOLGA8A golgin A8 family, member A
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HOXA5 homeobox A5
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL6ST interleukin 6 signal transducer
LAMP5 lysosomal-associated membrane protein family, member 5
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP4 low density lipoprotein receptor-related protein 4
MATN2 matrilin 2
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
N4BP2L2 NEDD4 binding protein 2-like 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PENK proenkephalin
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RBBP4 retinoblastoma binding protein 4
RPS27L ribosomal protein S27-like
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SKAP2 src kinase associated phosphoprotein 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SOX4 SRY (sex determining region Y)-box 4
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TMEM243 transmembrane protein 243, mitochondrial