BRD-K09638361_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K09638361_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CAPN2 calpain 2, (m/II) large subunit
CAV2 caveolin 2
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNN2 calponin 2
COTL1 coactosin-like F-actin binding protein 1
CTGF connective tissue growth factor
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
ELANE elastase, neutrophil expressed
ENAH enabled homolog (Drosophila)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
EREG epiregulin
FOSL1 FOS-like antigen 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GATA6 GATA binding protein 6
GLIPR1 GLI pathogenesis-related 1
HBEGF heparin-binding EGF-like growth factor
HOMER3 homer scaffolding protein 3
JMJD6 jumonji domain containing 6
KRT81 keratin 81, type II
LGALS4 lectin, galactoside-binding, soluble, 4
MIR22HG MIR22 host gene
MMP12 matrix metallopeptidase 12
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
P3H2 prolyl 3-hydroxylase 2
PAWR PRKC, apoptosis, WT1, regulator
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEK2 pleckstrin 2
PTPRE protein tyrosine phosphatase, receptor type, E
RAP1GAP RAP1 GTPase activating protein
TCL1A T-cell leukemia/lymphoma 1A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TUBB2A tubulin, beta 2A class IIa
VEGFA vascular endothelial growth factor A
ZNF91 zinc finger protein 91
ZYX zyxin

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR1C3 aldo-keto reductase family 1, member C3
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AQP3 aquaporin 3 (Gill blood group)
ATP9A ATPase, class II, type 9A
B3GNT1
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CPNE3 copine III
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSTA cystatin A (stefin A)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHFR dihydrofolate reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUT deoxyuridine triphosphatase
EAPP E2F-associated phosphoprotein
ESR1 estrogen receptor 1
FAM63A family with sequence similarity 63, member A
GATA3 GATA binding protein 3
H2AFX H2A histone family, member X
HADH hydroxyacyl-CoA dehydrogenase
HOXC10 homeobox C10
HOXC6 homeobox C6
IFI44L interferon-induced protein 44-like
KIAA0101 KIAA0101
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LTF lactotransferrin
MANSC1 MANSC domain containing 1
MCM2 minichromosome maintenance complex component 2
MELK maternal embryonic leucine zipper kinase
MREG melanoregulin
MSH6 mutS homolog 6
MUC1 mucin 1, cell surface associated
NUSAP1 nucleolar and spindle associated protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PEX11A peroxisomal biogenesis factor 11 alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RNASE4 ribonuclease, RNase A family, 4
RRM2 ribonucleotide reductase M2
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SEPP1 selenoprotein P, plasma, 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TRAPPC4 trafficking protein particle complex 4
TRD T cell receptor delta locus
TRPS1 trichorhinophalangeal syndrome I
TUBB tubulin, beta class I
TXNIP thioredoxin interacting protein
TYMS thymidylate synthetase
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UNG uracil-DNA glycosylase
VCAM1 vascular cell adhesion molecule 1
XBP1 X-box binding protein 1
ZWINT ZW10 interacting kinetochore protein